Products Dinutuximab was approved in the United States and the EU in 2015 as a concentrate for the preparation of an infusion solution (Unituxin). It has not yet been registered in many countries. Structure and properties Dinutuximab is a chimeric monoclonal antibody (human/mouse). Effects Dinutuximab (ATC L01XC16) has cytotoxic properties. It binds to ganglioside GD2, … Dinutuximab
Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies
Products Chitosan is available in many countries in the form of tablets and capsules. It is not marketed as a drug, but as a medical device or food supplement. Chitosan is also used as a pharmaceutical excipient, for wound dressings and numerous other purposes. This article refers to its use against obesity. Structure and properties … Chitosan
Products Hydrochlorothiazide is commercially available in numerous antihypertensive agents in combination with ACE inhibitors, sartans, renin inhibitors, potassium-sparing diuretics, calcium channel blockers, and beta blockers. Use as a monopreparation (Esidrex) is less common. Hydrochlorothiazide has been approved in many countries since 1958. Structure and properties Hydrochlorothiazide (C7H8ClN3O4S2, Mr = 297.7 g/mol) is a white crystalline … Hydrochlorothiazide
Products Ivermectin is commercially available in some countries in tablet form (Stromectol). It has not yet been registered in many countries and therefore must be imported from abroad if needed. Ivermectin has been used medicinally since the 1980s, initially primarily as a veterinary drug. This article refers to peroral administration in humans. See also under … Ivermectin
Introduction In most cases, the term “vasectomy” refers to the cutting of the male vas deferens. Vasectomy is a simple surgical procedure with few complications, which leads to very safe contraception. The number of procedures is increasing; in the USA it is already one of the most frequently used contraceptive measures. Vasectomies are also increasingly … Side effects of vasectomy
The renewed fertility Vasectomy is on the one hand a very safe contraceptive measure, but in exceptional cases it can nevertheless be accompanied by a renewed ability to procreate. The sperm duct is interrupted by the vasectomy for several centimeters and the ends are sutured. Under certain circumstances, however, the ends of the spermatic ducts … The renewed fertility | Side effects of vasectomy
Products Mefenamic acid is commercially available in the form of film-coated tablets, capsules, suppositories, and oral suspension. The drug has been approved in many countries since 1965. In addition to the original Ponstan, various generics are available. In many countries, the drug is known to both specialists and the general public and is frequently taken. … Mefenamic Acid
Products The first therapeutic monoclonal antibody was approved in 1986. Muromonab-CD3 (Orthoclone OKT3) binds to the CD3 receptor on T cells and has been used in transplantation medicine. Numerous drugs containing antibodies are now available. A selection of active substances can be found at the end of this article. These are expensive drugs. For example, … Monoclonal Antibodies
Products Taliglucerase alfa is commercially available as an infusion preparation in some countries (Elelyso). It has not yet been registered in many countries. Structure and properties Taliglucerase alfa is an enzyme and an analog of natural glucocerebrosidase, from which it differs in several amino acids. Glycosylation with mannose results in the uptake of taliglucerase alfa … Taliglucerase Alfa
Products Tamsulosin is commercially available in the form of sustained-release tablets and sustained-release capsules and has been approved in many countries since 1996 (Pradif, Pradif T, generics). Tamsulosin is also available as a fixed combination with the 5alpha-reductase inhibitor dutasteride (Duodart), see under dutasteride tamsulosin. In 1996, sustained-release capsules were released (Pradif). Pradif T sustained-release … Tamsulosin
Products Loratadine is commercially available in tablet form (Claritine, Claritine Pollen, generics). It has been approved in many countries since 1991. The active metabolite desloratadine is also available (Aerius, generics). Structure and properties Loratadine (C22H23ClN2O2, Mr = 382.9 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug … Loratadine
