Products Eribulin is commercially available as a solution for injection (Halaven). It was approved in many countries and in the EU in 2011. In the United States, it has been registered since 2010. Structure and properties Eribulin is present in drugs as eribulin mesilate (C40H59NO11 – CH4O3S, Mr = 826.0 g/mol), a white crystalline powder … Eribulin
Products Risankizumab was approved in the United States and in many countries in 2019 as a solution for injection (Skyrizi). Structure and properties Risankizumab is a humanized IgG1 monoclonal antibody produced by biotechnological methods. Effects Risankizumab (ATC L04AC) has selective immunosuppressive and anti-inflammatory properties. The antibody binds to the p19 subunit of human interleukin-23 (IL-23), … Risankizumab
Products Risedronate is available as weekly 35 mg tablets and as 30 mg tablets (Actonel, generic). Actonel 5 mg and 75 mg tablets are off-label in many countries. Risedronate has been approved since 2000. Generic versions went on sale in 2012. Structure and properties Risedronate (C7H10NO7P2Na – 2.5 H2O, Mr = 350.1 g/mol) is a … Risedronate
Products Ritonavir is commercially available as a monopreparation in the form of film-coated tablets (Norvir). It was approved in many countries, in the United States and in the EU in 1996, and is also used as a pharmacokinetic booster in combination with antiviral agents (eg, lopinavir). Norvir syrup is no longer marketed in many countries. … Ritonavir
Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan
Products Dihydroergocriptine is no longer registered in many countries. Cripar is out of commerce. Effects Dihydroergocriptine (ATC N04BC03) is dopaminergic and acts selectively on D2 receptors. It has no activity on serotoninergic or adrenergic receptors. Indications Parkinson’s disease Early stages of Parkinson’s disease, as monotherapy or in combination with an L-dopa preparation. Interval treatment of … Dihydroergocriptine
Products The marketing of medicinal products containing dihydroergotamine has been discontinued in many countries (e.g., Dihydergot tablets and nasal spray, Ergotonin, Effortil plus, Old Tonopan, and others). The approval of Dihydergot tablets was cancelled on February 1, 2014, because the benefits no longer outweighed the potential risks, according to drug regulators. Structure and properties Dihydroergotamine … Dihydroergotamine
Products Dihydropyridines are commercially available in many countries in the form of film-coated tablets, sustained-release tablets, capsules, and injectables. Nifedipine from Bayer (Adalat) was the first active ingredient from this group to enter the market in the mid-1970s. Today, amlodipine (Norvasc, generics) is most commonly prescribed. Structure and properties The name 1,4-dihydropyridines is derived from … Dihydropyridine
Products Dihydrotachysterol is commercially available as an oily solution (A.T. 10). It has been approved in many countries since 1952. Structure and properties Dihydrotachysterol (C28H46O, Mr = 398.7 g/mol) is a lipophilic analog of vitamin D. Effects Dihydrotachysterol (ATC A11CC02) has multiple properties in calcium metabolism. The compound is already active and does not need … Dihydrotachysterol
Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem
Products Pyrvinium is commercially available as an oral suspension and in the form of dragées. It is no longer available in many countries. Structure and properties Pyrvinium (C26H28N3+, Mr = 382.5 g/mol) is present in pharmaceuticals as pyrvinium embonate or pyrvinium pamoate. Pyrvinium embonate is an orange-red to orange-brown powder with almost no odor and … Pyrvinium
Application Mercury (Hydrargyrum, Hg) and its compounds are rarely used in pharmacy today because of their toxicity and adverse effects. An exception is alternative medicine, in which mercury is also called mercurius (e.g., Mercurius solubilis, Mercurius vivus). The English name is Mercury or Quicksilver. In the 20th century, mercury compounds were still widely used and … Mercury
