Products Medicines containing nedocromil are no longer available in many countries. The eye drops (Tilavist), nasal spray (Tilarin), and preparation for inhalation (Tilade) are out of commerce, presumably for commercial reasons. This article refers to ocular use. Structure and properties Nedocromil (C19H17NO7, Mr = 371.34 g/mol) belongs to the class of pyranoquinolines and is present … Nedocromil
Products Brinzolamide is form of eye drops commercially available (Azopt) and approved in many countries since 1991. Generic versions were released in 2015. Brinzolamide has also been available in a fixed combination with timolol since 2009 (Azarga). In 2015, a fixed combination with brimonidine was approved; see brinzolamide brimonidine (Simbrinza). Structure and properties Brinzolamide (C12H21N3O5S3, … Brinzolamide
Products Bromfenac is commercially available in the form of eye drops (Yellox). It was approved in the United States in 2005 and in the EU in 2011. It was registered in many countries in 2013. Structure and properties Bromfenac (C15H12BrNO3, Mr = 334.2 g/mol) is a benzophenone derivative. It is present in solution in drugs … Bromfenac
Products Tear substitutes are available as eye drops or eye gels in the form of single doses (monodoses, SDU, UD) and in vials. The monodoses do not contain preservatives and are usually suitable for contact lens wearers. The vials may contain a preservative and have a limited shelf life after opening. However, there are those … Tear Substitute
Products Trifluridine is commercially available in the form of eye drops and other products. This article relates to ocular therapy. Structure and properties Trifluridine (C10H11F3N2O5, Mr = 296.2 g/mol) is a fluorine derivative of thymidine and is therefore also known as trifluorothymidine. Effects Trifluridine (ATC S01AD02) has antiviral properties. It inhibits thymidic acid synthetase, viral … Trifluridine
Products Hexamidine eye drops have been approved in many countries since 1994 (Desomedin, Desomedin DD, Monodoses). The disinfectant is also present in skin creams (Imacort, Imazol) and cosmetics. Structure and properties Hexamidine (C20H26N4O, Mr = 354.5 g/mol) is present in drugs as hexamidine diisetionate, a white to pale yellow powder that is sparingly soluble in … Hexamidine Eye Drops
Products Eye drops containing antibiotics are available from various manufacturers in pharmacies. They are also combined with other active ingredients such as glucocorticoids fix. Structure and properties The drops contain antibiotics from different chemical groups (see below). Effects Depending on the active ingredient, the antibiotics have bacteriostatic to bactericidal properties, meaning they inhibit the growth … Antibiotic Eye Drops to treat Bacterial Eye Infections
Effects Antihistamine eye drops have antihistamine and antiallergic properties. They are more or less selective antagonists of histamine at the H1 receptor, abolish histamine effects and thus relieve symptoms such as itching, redness, swelling, and tearing. Compared with oral antihistamines, the effect occurs after only a few minutes and lasts up to 12 hours. Many … Antihistamine Eye Drops
Products Various eye drops and eye gels containing hyaluronic acid are commercially available. These are registered medicinal products (e.g., Lacrycon) and medical devices (e.g., Bepanthen eye drops). Structure and properties Hyaluronic acid is usually present in the preparations in the form of the sodium salt sodium hyaluronate. Sodium hyaluronate is a natural glycosaminoglycan composed of … Hyaluronic Acid Eye Drops
Products Ciclosporin eye drops were approved in the EU in 2015 and in many countries in 2016 (Ikervis). They have been registered in the United States since 2009 (Restasis). Structure and properties Ciclosporin (C62H111N11O12, Mr = 1203 g/mol) exists as a white powder that is practically insoluble in water. It is extracted from the mushroom … Ciclosporin Eye Drops
Products Prostaglandin analogues are commercially available in the form of eye drops in vials or as monodoses without preservatives. Latanoprost (Xalatan) was the first agent from this group to be approved in 1996. Prostaglandin analogues are also combined with the beta-blocker timolol fix. Structure and properties Prostaglandin analogs are derivatives of prostaglandin F2α. Except for … Prostaglandin Analogs
Products Timolol is commercially available in the form of eye drops and as an eye gel. In addition to the original Timoptic, generics and various fixed combinations with other antiglaucomatous agents are also commercially available (brinzolamide, brimonidine, dorzolamide, travoprost, latanoprost). Timolol has been approved in many countries since 1978. See also under timolol gel (hemangioma). … Timolol
