Pregabalin

Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin

Anxiolytics

Products Anxiolytics are commercially available in the form of tablets, capsules, and injectable preparations, among others. Structure and properties Anxiolytics are a structurally heterogeneous group. However, the representatives can be divided into different classes. These include, for example, the benzodiazepines or the tricyclic antidepressants. Effects Anxiolytics have antianxiety (anxiolytic) properties. They usually have additional effects, … Anxiolytics

Ketazolam

Products Ketazolam is commercially available in capsule form (Solatran). It has been approved in many countries since 1980. Structure and properties Ketazolam (C20H17ClN2O3, Mr = 368.8 g/mol) structurally belongs to the 1,4-benzodiazepines. Effects Ketazolam (ATC N05BA10) has antianxiety, depressant, muscle relaxant, and anticonvulsant properties. The effects are due to binding to GABA-A receptors and enhancement … Ketazolam

Hydromorphone

Products Hydromorphone is commercially available as sustained-release tablets, sustained-release capsules, capsules, solution for injection, solution for infusion, and drops (e.g., Palladon, Jurnista, Hydromorphoni HCl Streuli). It has been approved in many countries since 1996. Structure and properties Hydromorphone (C17H19NO3, Mr = 285.3 g/mol) is a semisynthetic, hydrogenated and oxidized morphine derivative. It is present in … Hydromorphone

Perphenazine

Products Perphenazine was commercially available in the form of film-coated tablets (Trilafon). It was approved in many countries in 1957 and went out of commerce on 3/31/2013. Structure and properties Perphenazine (C21H26ClN3OS, Mr = 403.9 g/mol) is a piperidine derivative of phenothiazine. It exists as a white to yellowish white crystalline powder that is practically … Perphenazine

Cannabidiol

Products In many countries, there are currently no medicines approved that contain only cannabidiol. However, the active ingredient is a component of the cannabis oral spray Sativex, which is registered as a drug for MS treatment in many countries and also contains THC. The oral solution Epidiolex or Epidyolex was approved as a drug in … Cannabidiol

Cannabidiol Hemp

Products Hemp with a high content of cannabidiol and a low total content of tetrahydrocannabinol (less than 1%) can be legally sold in many countries since 2016 and is available from specialized suppliers and web stores. Cannabidiol hemp is approved as a tobacco substitute product and not yet as a medicine. Neither cannabidiol nor cannabidiol … Cannabidiol Hemp

Cannabinoid Receptor Antagonists

Products Cannabinoid receptor antagonists are no longer on the market in many countries. Rimonabant (Acomplia) was withdrawn from the market in 2008 because it can cause psychiatric disorders, particularly depression. Effects Cannabinoid receptor antagonists have appetite suppressant, lipid-lowering, antidiabetic, analgesic (antiallodynic, antinociceptive), and anti-inflammatory properties. The effects of cannabinoid receptor antagonists are largely opposite to … Cannabinoid Receptor Antagonists

Cannabis

Products Hemp and preparations made from it, such as marijuana, cannabis resin, THC, and cannabis extracts, are generally among the prohibited narcotics in many countries. However, the Federal Office of Public Health may grant exemptions for research, drug development and limited medical use. In 2013, a cannabis oral spray (Sativex) was approved as a medicine … Cannabis

Sleeping Pills: Effects, Side Effects, Dosage and Uses

Products Sleeping pills are most commonly taken in the form of tablets (“sleeping pills“). In addition, melting tablets, injectables, drops, teas and tinctures are also available, among others. The technical term hypnotics is derived from Hypnos, the Greek god of sleep. Structure and properties Within the sleeping pills, groups can be identified which have a … Sleeping Pills: Effects, Side Effects, Dosage and Uses

Bromazepam

Products Bromazepam is commercially available in tablet form (Lexotanil). It has been approved in many countries since 1974. Structure and properties Bromazepam (C14H10BrN3O, Mr = 316.2 g/mol) exists as a white to yellowish crystalline powder that is practically insoluble in water. It is a brominated 1,4-benzodiazepine. Effects Bromazepam (ATC N05BA08) has antianxiety, sedative, and depressant … Bromazepam

Ethanol

Products Alcohol is contained in numerous intoxicating and stimulant products, such as wines, sparkling wines, beers and high-proof spirits. Per capita consumption in many countries averages about 8 liters of pure alcohol per year. Ethanol is also available as an open product in various qualities in pharmacies and drugstores (e.g. ethanol 70% with camphor, ethanol … Ethanol