Products Finasteride is commercially available as film-coated tablets (prostate: Proscar, generic, 5 mg; hair loss: Propecia, generic, 1 mg). It has been approved in many countries since 1993. Propecia was launched five years later, in 1998. Structure and properties Finasteride (C23H36N2O2, Mr = 372.5 g/mol) is a 4-azasteroid and structurally related to testosterone. It exists … Finasteride
Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron
Products Epinastine is commercially available in the form of eye drops (Relestat). It has been approved in many countries since 2004. Structure and properties Epinastine (C16H15N3, Mr = 249.31 g/mol) is present in drugs as epinastine hydrochloride. It is an azepine and imidazole derivative. Effects Epinastine (ATC S01GX10) has antihistamine, antiallergic, and mast cell stabilizing … Epinastine
Products Bicalutamide is commercially available in the form of film-coated tablets (Casodex, generics). It has been approved in many countries since 1995. Structure and properties Bicalutamide (C18H14F4N2O4S, Mr = 430.37 g/mol) is a racemate, with the -enantiomer being almost exclusively responsible for the antiandrogenic effect. It exists as a white powder that is practically insoluble … Bicalutamide
Products Tamsulosin is commercially available in the form of sustained-release tablets and sustained-release capsules and has been approved in many countries since 1996 (Pradif, Pradif T, generics). Tamsulosin is also available as a fixed combination with the 5alpha-reductase inhibitor dutasteride (Duodart), see under dutasteride tamsulosin. In 1996, sustained-release capsules were released (Pradif). Pradif T sustained-release … Tamsulosin
Products Dutasteride is commercially available in capsule form (Avodart). It is also available in combination with the alpha blocker tamsulosin (Duodart); see dutasteride tamsulosin. The active ingredient has been approved in many countries since 2003. Generics were registered in 2017. Generic versions of Duodart were approved in 2018. Structure and properties Dutasteride (C27H30F6N2O2, Mr = … Dutasteride
Products The 5alpha-reductase inhibitor dutasteride and the alpha-blocker tamsulosin are commercially available as a fixed combination in the form of capsules (Duodart, generics). The drug has been approved in many countries since 2010. Structure and properties Dutasteride (C27H30F6N2O2, Mr = 528.5 g/mol) is a 4-azasteroid and structurally closely related to finasteride. It exists as a … Dutasteride, Tamsulosin
Products Serotonin receptor antagonists are commercially available in the form of film-coated tablets, melting tablets, soft capsules, as syrups, and as infusion/injection preparations. This article refers to the setrone (5-HT3 receptor antagonists), which are used as antiemetics. The first agent from this group to be approved in the United States was ondansetron (Zofran) in 1991, … Serotonin Antagonists (Setrone)
Products Naloxone is commercially available as a solution for injection (Naloxone OrPha, Naloxone Actavis) and has been approved in many countries since 2004. Information on combination with oxycodone is presented under the article Oxycodone and Naloxone (Targin, Peroral). As a fixed combination with buprenorphine, naloxone is used to treat opioid dependence (Suboxone, sublingual). In 2014, … Naloxone