Coronavirus vaccination: Why waiting is so dangerous

If you don’t get vaccinated, you’ll get infected Since the highly contagious delta variant has determined the pandemic, one thing is clear with a high degree of probability: anyone who does not get vaccinated will become infected with Sars-CoV-2. According to experts, herd immunity that also protects the unvaccinated can no longer be expected with … Coronavirus vaccination: Why waiting is so dangerous

COVID-19: Answers for the Post-Vaccination Period

When does the vaccination start to take effect? For the vaccines currently approved in Germany to fully develop their protective effect, two injections are usually necessary. An exception is the vaccine from the manufacturer Janssen (Johnson & Johnson): A single dose of vaccine is sufficient for full protection. With the AstraZeneca preparation, the best possible … COVID-19: Answers for the Post-Vaccination Period

Omikron: Omicron

Omikron XBB.1.5 – the super variant The Omikron XBB.1.5 subline is currently spreading rapidly in the USA and could soon dominate the infection scene in Europe as well. The variant is also referred to as the “octopus”. It appears to be the most infectious variant of Sars-CoV-2 to date. Genetic mix of two omicron variants … Omikron: Omicron

Azithromycin

Products Azithromycin is commercially available in the form of film-coated tablets, powder for preparation of a suspension, and granules (Zithromax, generic). Furthermore, a granule for the preparation of a sustained-release oral suspension is available (Zithromax Uno). Eye drops have also been released in some countries. Azithromycin has been approved in many countries since 1992. Structure … Azithromycin

Sputnik V

Products Sputnik V is a Covid-19 vaccine developed in Russia and the first vaccine from this group to be registered on August 11, 2020 (Gamaleya National Center of Epidemiology and Microbiology). The name is derived from the Sputnik satellite, which was the first satellite placed in Earth orbit by the Soviet Union in 1957. Sputnik … Sputnik V

COVID-19

Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19

APN01 (Recombinant ACE2)

Products APN01 is in clinical development at Apeiron Biologics. Structure and properties APN01 is a recombinant, soluble, and human angiotensin-converting enzyme 2 (ACE2). Effects APN01 functions as a false receptor for the coronavirus SARS-CoV-2, the causative agent of the viral disease Covid-19. SARS-CoV-2 uses ACE2 for attachment and entry into host cells. APN01 is a … APN01 (Recombinant ACE2)

AZD1222

Products AZD1222 has been in the registration phase in the EU and many countries since the beginning of October 2020 as part of a rolling review and is not yet commercially available. The vaccine was developed at Oxford University’s Jenner Institute, spin-off Vaccitech and AstraZeneca. Efficacy and safety are being evaluated in studies involving up … AZD1222

Favipiravir

Products Favipiravir is approved in Japan in the form of film-coated tablets (Avigan). Structure and properties Favipiravir (C5H4FN3O2, Mr = 157.1 g/mol) is a fluorinated pyrazine carboxamide derivative. It is a prodrug that is biotransformed in cells to the active metabolite favipiravir-RTP (favipiravir-ribofuranosyl-5′-triphosphate), a purine nucleotide analog. Favipiravir exists as a white to slightly yellow … Favipiravir

Hydroxychloroquine

Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine

MRNA-1273

Products mRNA-1273 enters the market as a white dispersion in multidose containers. It was licensed in the EU on January 6, 2021, and in many countries on January 12, 2021. The vaccine has been studied in a clinical trial involving more than 30,000 participants. The unopened multi-dose vial can be stored at -15 °C to … MRNA-1273