Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses
Products Indinavir is commercially available in capsule form (Crixivan). It has been approved in many countries since 1996. Structure and properties Indinavir (C36H47N5O4, Mr = 613.8 g/mol) is present in drugs as indinavir sulfate, a white crystalline powder that is very soluble in water. Effects Indinavir (ATC J05AE02) has antiviral properties. The effects are due … Indinavir
Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate
Products 5α-Reductase inhibitors are commercially available in many countries in the form of film-coated tablets and capsules. Finasteride was the first agent from this group to be approved in 1993 (USA: 1992). There are two finasteride drugs on the market. One with 5 mg for the treatment of prostate enlargement (Proscar, generic) and one with … 5Α-Reductase Inhibitors
Products Sunitinib is commercially available in capsule form (Sutent). It has been approved in many countries since 2006. Structure and properties Sunitinib (C22H27FN4O2, Mr = 398.5 g/mol) is present in the drug as sunitinibmalate, a yellow to orange powder that is soluble in water. It is an indolin-2-one and pyrrole derivative. It has an active … Sunitinib
Products The fixed combination of netupitant and palonosetron has been approved in capsule form (Akynzeo). The drug was released in many countries in 2015. Structure and properties Netupitant (C30H32F6N4O, Mr = 578.6 g/mol) is a fluorinated piperazine and pyrimidine derivative. Palonosetron (C19H24N2O, Mr = 296.4 g/mol) is present in drugs as palonosetron hydrochloride, a white … Netupitant, Palonosetron
Products Fusidic acid is commercially available as film-coated tablets, cream, ointment, gauze, and ophthalmic drip gel (including Fucidin, Fucithalmic, and generics). It has been approved in many countries since 1968. See also under fusidic acid eye gel. Structure and properties Fusidic acid (C31H48O6, Mr = 516.7 g/mol) belongs to the steroid antibiotics. It is obtained … Fusidic Acid
Products Exemestane is commercially available in the form of dragées and film-coated tablets (Aromasin, generics). It has been approved in many countries since 1999. Structure and properties Exemestane (C20H24O2, Mr = 296.4 g/mol), unlike other aromatase inhibitors, has a steroidal structure and resembles the natural substrate androstenedione. It exists as a white to slightly yellowish … Exemestane
Products Abametapir was approved in the United States in 2020 as an emulsion for external use (Xeglyze). Structure and properties Abametapir (C12H12N2, Mr = 184.24 g/mol) consists of two molecules of methylpyridine covalently bonded together. The active ingredient is present as an oil-in-water emulsion. Effects Abametapir has insecticidal and ovicidal properties, meaning it kills both … Abametapir
Products Abemaciclib was approved in the form of film-coated tablets in the United States in 2017, in the EU in 2018, and in many countries in 2019 (Verzenios). Structure and properties Abemaciclib (C27H32F2N8, Mr = 506.6 g/mol) exists as a white to yellow powder. Effects Abemaciclib (ATC L01XE50) has antitumor and antiproliferative properties. The effects … Abemaciclib
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin
