Stem plant Loranthaceae, mistletoe. Medicinal drug Visci albi herba (Visci herba) – mistletoe herb. Ingredients Lectins Polypeptides Flavonoids Lignans Biogenic amines Effects Cytostatic Immunostimulatory Blood pressure lowering ? Fields of application In anthroposophic medicines for malignant tumors. In folk medicine for hypertension. Dosage In finished medicines, according to the manufacturer mistletoe tincture: 15 – 20 … Mistletoe: Medicinal Uses
Products Mitomycin is commercially available as a powder for the preparation of a solution for injection or infusion (Mitem). Structure and properties Mitomycin (C15H18N4O5, Mr = 334.3 g/mol) exists as a blue-violet crystalline powder or as crystals and is sparingly soluble in water. It is formed by a strain of. Mitomycin was first isolated in … Mitomycin
Products Ingenol mebutate was commercially available as a gel (Picato). It was approved in many countries in 2013, and in the EU and the U.S. as early as 2012. In 2020, approval was withdrawn because an increased risk of skin cancer was observed with the treatment. Structure and properties Ingenol mebutate (C25H34O6, Mr = 430.5 … Ingenol Mebutate
Products 5-Fluorouracil is commercially available as an ointment (Efudix), as a topical solution in combination with salicylic acid (Verrumal), and in preparations for parenteral administration. This article refers to topical application. In 2011, 5-fluorouracil at the lower concentration of 0.5% was approved in many countries with Actikerall. Structure and properties 5-Fluorouracil (C4H3FN2O2, Mr = 130.08 … 5-Fluorouracil
Products Melphalan is commercially available in the form of film-coated tablets and as an injection/infusion preparation (Alkeran). It has been approved in many countries since 1964. Structure and properties Melphalan (C13H18Cl2N2O2, Mr = 305.2 g/mol) is a phenylalanine derivative of nitrogen-lost. It is practically insoluble in water. It exists as a pure L-enantiomer. The racemate … Melphalan
Products Carboplatin is commercially available as an infusion solution (paraplatin, generic). It has been approved in many countries since 1986. Structure and properties Carboplatin (C6H12N2O4Pt, Mr = 371.3 g/mol) is a platinum compound. It exists as a colorless crystalline powder that is sparingly soluble in water. Carboplatin is structurally related to cisplatin, the first platinum … Carboplatin
Products Dasatinib is commercially available in the form of film-coated tablets (Sprycel). It has been approved in many countries since 2007. Generic versions were registered in 2020. Structure and properties Dasatinib (C22H26ClN7O2S, Mr = 488.0 g/mol) exists as a white powder that is insoluble in water. It is an aminopyrimidine derivative. Effects Dasatinib (ATC L01XE06) … Dasatinib
Products Gemcitabine is commercially available as a lyophilizate for the preparation of an infusion solution (Gemzar, generics). It has been approved in many countries since 1997. Structure and properties Gemcitabine (C9H11F2N3O4, Mr = 263.2 g/mol) is present in drugs as gemcitabine hydrochloride, a white substance that is soluble in water. The pyrimidine gemcitabine is a … Gemcitabine
Products Alectinib was approved in capsule form in Japan in 2014, in the United States in 2015, and in many countries in 2017 (Alecensa). Structure and properties Alectinib (C30H34N4O2, Mr = 482.6 g/mol) is present in the drug product as alectinib hydrochloride, a white to yellow-white powder. It has an active metabolite (M4). Effects Alectinib … Alectinib
Products Gefitinib is commercially available in the form of film-coated tablets (Iressa). It was approved in many countries in 2011. Structure Gefitinib (C22H24ClFN4O3, Mr = 446.9 g/mol) is a morpholine and aniline quinazoline derivative. It exists as a white powder that is sparingly soluble in water, especially at high pH. Effects Gefitinib (ATC L01XE02) is … Gefitinib
Products Hydroxycarbamide is commercially available in the form of capsules (Litalir, generics). It has been approved in many countries since 1995. Structure and properties Hydroxycarbamide (CH4N2O2, Mr = 76.1 g/mol) is a hydroxylated urea (-hydroxyurea). It exists as a white, crystalline, hygroscopic powder that is readily soluble in water. Effects Hydroxycarbamide (ATC L01XX05) is cytostatic. … Hydroxycarbamide
Products Pemetrexed is commercially available as an infusion drug (Alimta, generic). It has been approved in many countries since 2005. Structure and properties Pemetrexed (C20H21N5O6, Mr = 427.4 g/mol) is a folic acid analog. It is present in drugs hydrated and as a disodium salt, in the original preparation as pemetrexed disodium heptahydrate, a white … Pemetrexed
