drug interactions

Serotonin Syndrome: Causes, Treatment

Brief overview Symptoms: Profuse sweating, reddened skin, dry mucous membranes, high pulse and blood pressure, nausea and vomiting, disturbances between muscles and nerves (tremors, muscle rigidity, excessive reflexes), psychological disturbances (restlessness, agitation, impaired consciousness) as well as cardiac arrhythmias, epileptic seizures and organ failure Treatment: discontinuation of causative medications, extensive cooling if fever is high, … Serotonin Syndrome: Causes, Treatment

Cistus

Products Products available in pharmacies and drugstores include the medicinal drug, lozenges, and teas (e.g., Cystus 052, Phytopharma Infectblocker). Stem plant Stem plants include several species and varieties from the genus Cistus and the family Cistaceae, which are native to southern Europe and the Mediterranean region. In many countries, especially the herb of and of … Cistus

Oxcarbazepine

Products Oxcarbazepine is available in the form of film-coated tablets, sustained-release tablets, and as a suspension and commercially (Trileptal, Apydan extent). It has been approved in many countries since 1997. Structure and properties Oxcarbazepine (C15H12N2O2, Mr = 252.3 g/mol) exists as a white to faint orange crystalline powder and is practically insoluble in water. Oxcarbazepine … Oxcarbazepine

Rivastigmine

Products Rivastigmine is commercially available as capsules, oral solution, and transdermal patch (Exelon, generics). It has been approved in many countries since 1997. Structure and properties Rivastigmine (C14H22N2O2, Mr = 250.3 g/mol) is a phenyl carbamate. It exists in the oral forms as rivastigmine hydrogenotartrate, a white crystalline powder that is very soluble in water. … Rivastigmine

Rizatriptan

Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan

Dihydrotachysterol

Products Dihydrotachysterol is commercially available as an oily solution (A.T. 10). It has been approved in many countries since 1952. Structure and properties Dihydrotachysterol (C28H46O, Mr = 398.7 g/mol) is a lipophilic analog of vitamin D. Effects Dihydrotachysterol (ATC A11CC02) has multiple properties in calcium metabolism. The compound is already active and does not need … Dihydrotachysterol

Diltiazem

Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem

Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

Mirabegron

Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron

Nadroparin

Products Nadroparin is commercially available as a solution for injection (Fraxiparine, Fraxiforte). It has been approved in many countries since 1988. Structure and properties Nadroparin is present in the drug as nadroparin calcium. It is the calcium salt of a low-molecular-weight heparin obtained by depolymerization of heparin from the intestinal mucosa of pigs using nitrous … Nadroparin

Bismuth, Metronidazole, Tetracycline

Products The fixed combination Pylera with the active ingredients bismuth, metronidazole, and tetracycline was approved in many countries in 2017 in the form of hard capsules. In some countries, it was available much earlier, for example, in the United States since 2006. This treatment is the so-called bismuth quadruple therapy (“BMTO”), which was developed by … Bismuth, Metronidazole, Tetracycline

Amorolfine

Products Amorolfine is commercially available for the treatment of a nail fungus as a nail polish (Loceryl, Curanel, 5%, generic). It has been approved in many countries since 1991. Curanel was released in April 2011 and, unlike Loceryl, is available without a doctor’s prescription. It is also sold as Curanail in other countries. In 2014, … Amorolfine