Products Amphotericin B is available in tablet, lozenge, suspension, and injection forms (Ampho-Moronal, Fungizone). It has been approved in many countries since 1964. This article refers to its use in the mouth and digestive system. Structure and properties Amphotericin B (C47H73NO17, Mr = 924 g/mol) is a mixture of antifungal polyenes obtained from certain strains … Amphotericin B: Effects and Side Effects
Products Sulfasalazine is commercially available as tablets and as dragées with an enteric coating (salazopyrin, salazopyrin EN, some countries: azulfidine, azulfidine EN, or RA). It has been approved in many countries since 1950. EN stands for enteric coated and RA for Rheumatoid Arthritis. EN dragées have a coating to prevent irritation and improve gastric tolerance. … Sulfasalazine: Drug Effects, Side Effects, Dosage and Uses
Definition Prescription drugs are a group of drugs that may be obtained from a pharmacy only with a doctor’s prescription. The prescription is usually issued during a consultation. Within this group, different dispensing categories exist in many countries. The presence of a doctor’s prescription is often a condition for the health insurance company to reimburse … Prescription Drugs
Products The fixed combination of netupitant and palonosetron has been approved in capsule form (Akynzeo). The drug was released in many countries in 2015. Structure and properties Netupitant (C30H32F6N4O, Mr = 578.6 g/mol) is a fluorinated piperazine and pyrimidine derivative. Palonosetron (C19H24N2O, Mr = 296.4 g/mol) is present in drugs as palonosetron hydrochloride, a white … Netupitant, Palonosetron
Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine
Products Melatonin is commercially available in the form of sustained-release tablets (Circadin, Slenyto). It was approved as a prescription drug in the EU in 2007 and in many countries in 2009. Melatonin may also be included in magistral formulations. Slenyto was registered in many countries in 2019. In some countries – for example, the United … Melatonin: Drug Effects, Side Effects, Dosage and Uses
Products Melatonin receptor agonists are commercially available in tablet and capsule form. Structure and properties Melatonin receptor agonists are structurally derived from and related to the natural hormone melatonin. Effects Melatonin, a sleep hormone produced by the pineal (pineal) gland of the brain from tryptophan, has a central role in the body in regulating the … Melatonin Receptor Agonists
Products Lymecycline is commercially available in the form of capsules (Tetralysal). It was approved in many countries in 2005. Structure and properties Lymecycline (C29H38N4O10, Mr = 602.6 g/mol) is a water-soluble prodrug of the antibiotic tetracycline with the amino acid lysine. Lymecycline is better absorbed than tetracycline. Effects Lymecycline (ATC J01AA04) has bacteriostatic properties against … Lymecycline
Products Lysozyme is mainly commercialized in medicines for sore throat, e.g., Lysopain and Sangerol. Structure and properties Lysozyme is an endogenous mucopolysaccharidase (protein, enzyme) found in saliva and elsewhere. It is composed of 129 amino acids. Effects Lysozyme (ATC A01AB11) has bactericidal, antiviral, and anti-inflammatory properties. Indications Acute inflammatory conditions of the mouth and throat, … Lysozyme
Products Abametapir was approved in the United States in 2020 as an emulsion for external use (Xeglyze). Structure and properties Abametapir (C12H12N2, Mr = 184.24 g/mol) consists of two molecules of methylpyridine covalently bonded together. The active ingredient is present as an oil-in-water emulsion. Effects Abametapir has insecticidal and ovicidal properties, meaning it kills both … Abametapir
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin
