Products The pure tea tree oil is available in pharmacies and drugstores. There are numerous products with the essential oil on the market, for example, body care products, lip balms, mouthwashes and toothpastes. These are usually not registered medicines. Structure and properties Tea tree oil is the essential oil obtained by steam distillation from the … Tea Tree Oil: Medicinal Uses
Products Ciprofloxacin is commercially available as film-coated tablets, oral suspension, infusion preparation, eye drops, eye ointment (Ciloxan), and ear drops (Ciproxin HC + hydrocortisone). In addition to the original Ciproxin, various generics are available. Ciprofloxacin was approved in many countries in 1987. This article refers to peroral administration. Structure and Properties Ciprofloxacin (C17H18FN3O3, Mr = … Ciprofloxacin
Effect Nitroimidazoles are antibacterial (bactericidal) and antiparasitic. They are reduced under anaerobic conditions to cytotoxic metabolites that covalently bind to and damage DNA. The damage may take the form of loss of helical structure, impaired matrix function, or strand breaks, leading to inhibition of DNA synthesis. Indications Spectrum: gram-positive and gram-negative anaerobic bacteria and some … Nitroimidazole
Structure and properties Doripenem (C15H24N4O6S2, Mr = 420.5 g/mol) exists as doripenem monohydrate, a white to slightly yellow crystalline powder. It bears a 1-β-methyl group that protects it from degradation by dehydropeptidase I. Effects Doripenem (ATC J01DH04) is bactericidal against numerous aerobic and anaerobic Gram-positive and Gram-negative bacteria. Its effects are based on inhibition of … Doripenem
Products Ertapenem is commercially available as a lyophylisate for the preparation of an infusion solution (Invanz). It has been approved in many countries since 2003. Structure and properties Ertapenem (C22H25N3O7S, Mr = 475.5 g/mol) is present in drugs as ertapenem sodium, a white, hygroscopic, weakly crystalline powder that is soluble in water. It is a … Ertapenem
Products Cefovecin is available as an injectable for animals. It has been approved in many countries since 2007. Structure and properties Cefovecin (C17H19N5O6S2, Mr = 453.5 g/mol) Effects Cefovecin (ATCvet QJ01DD91) has bactericidal properties with long-lasting activity against Gram-positive and Gram-negative bacteria. Indications For the treatment of bacterial infectious diseases in dogs and cats.
Products Cefpodoxime is commercially available as film-coated tablets and as granules for preparation of a suspension (Podomexef, generics). It has been approved in many countries since 1991. Structure and properties Cefpodoxime (C15H17N5O6S2, Mr = 427.5 g/mol) is present in drugs as cefpodoxime proxetil. It is an ester prodrug and is rapidly converted to cefpodoxime in … Cefpodoxime
Products Ceftarolinefosamil is commercially available as a powder for the preparation of a concentrate for an infusion solution (Zinforo). It has been approved in many countries since 2013. Structure and properties Ceftarolinefosamil (C22H21N8O8PS4, Mr = 684.7 g/mol) is present in drugs as ceftarolinefosamil monoacetate monohydrate, a yellowish-white powder. Ceftarolinefosamil is a prodrug that is enzymatically … Ceftarolinefosamil
Products Bacitracin is used for topical therapy, for example, in the form of ointments and eye ointments. It is also combined with neomycin, which is effective against Gram-negative bacteria. The bacteria that form bacitracin were first isolated in the 1940s from a contaminated wound on the shin of a girl named Margaret Treacy (Johnson et … Bacitracin
Symptoms Meningococcus can cause a life-threatening meningitis, called meningococcal meningitis, and blood poisoning, called meningococemia. The three typical symptoms of meningitis include fever, severe headache and neck stiffness. Other possible symptoms include nausea, vomiting, photophobia, and neurological disorders such as confusion. In infants and young children, symptoms may be absent or difficult to recognize. Sepsis … Meningococcus
Products Ceftibuten was commercially available in many countries as a powder for preparation of a suspension and in capsule form (Cedax). It had been approved in many countries since 1994. Structure and properties Ceftibuten (C15H14N4O6S2, Mr = 410.4 g/mol) is present in drugs anhydrous or as ceftibutene dihydrate. Effects Ceftibuten (ATC J01DA39) has bactericidal properties … Ceftibuten
Products Ceftobiprole was approved in many countries in 2009 as a powder for a concentrate for the preparation of an infusion solution (Zevtera). Structure and properties Ceftobiprole (C20H22N8O6S2, Mr = 534.6 g/mol) is present in the drug in the form of the prodrug ceftobiprole medocaril and as a sodium salt. The prodrug is converted to … Ceftobiprole