Products Ceftobiprole was approved in many countries in 2009 as a powder for a concentrate for the preparation of an infusion solution (Zevtera). Structure and properties Ceftobiprole (C20H22N8O6S2, Mr = 534.6 g/mol) is present in the drug in the form of the prodrug ceftobiprole medocaril and as a sodium salt. The prodrug is converted to … Ceftobiprole
Products Cefuroxime is commercially available as film-coated tablets, powder for suspension, and injectable (Zinat, Zinacef, Aprokam, generics). It has been approved in many countries since 1988. Structure and properties Cefuroxime (C16H15N4NaO8S, Mr = 446.4 g/mol) is present in peroral drugs in the form of the acetoxyethyl ester prodrug cefuroxime axetil, a white powder that is … Cefuroxime
Symptoms Legionellosis manifests itself in the following symptoms: Cough, shortness of breath Severe pneumonia High fever, chills Muscle pain, aching limbs Headache Legionellosis can lead to severe complications such as respiratory failure and death. Mortality is relatively high. Pontiac fever is a mild infection with Legionella, which lasts only about a week and runs without … Legionellosis
Products Grepafloxacin is no longer commercially available because of potential adverse effects. Raxar or Vaxar film-coated tablets were withdrawn from the market in 1999. Structure and properties Grepafloxacin (C19H22FN3O3, Mr = 359.4 g/mol) is present in drugs as grepafloxacin hydrochloride. Effects Grepafloxacin (ATC J01MA11) has bactericidal properties against Gram-positive and Gram-negative pathogens. The effects are … Grepafloxacin
Products Doxycycline is commercially available in the form of tablets, capsules, and as a solution for injection (vibramycin, vibravenous, generic). It has been approved in many countries since 1972. Structure and properties Doxycycline (C22H24N2O8, Mr = 444.4 g/mol) is usually present in drugs as doxycycline hyclate. Some drugs also contain doxycycline monohydrate. These are yellow … Doxycycline: Drug Effects, Side Effects, Dosage and Uses
Products Rifampicin is commercially available as film-coated tablets, coated tablets, capsules, and injectables (Rimactan, generics). In addition to mono, various combination preparations are also available. Rifampicin has been approved in many countries since 1968. This article refers to peroral monotherapy. Structure and properties Rifampicin (C43H58N4O12, Mr = 823 g/mol) exists as a reddish brown to … Rifampicin
Products Rifaximin is commercially available in the form of film-coated tablets (Xifaxan). It was approved in many countries in 2015. In many countries, it was available earlier. Rifaximin was first released in Italy in the 1980s. Structure and properties Rifaximin (C43H51N3O11, Mr = 785.9 g/mol) is a semisynthetic pyridoimidazole derivative of rifamycin. It exists as … Rifaximin
Products Tylosin is commercially available as a solution for injection and in the form of drug premixes as a veterinary drug (Tylan). Combination preparations with chloramphenicol and sulfadimidine are also available. It has been approved in many countries since 1967 and exclusively as a veterinary drug. Structure and properties Tylosin (C46H77NO17, Mr = 916.1 g/mol) … Tylosin
Products Clindamycin is commercially available in several dosage forms. This article refers to oral administration with capsules (Dalacin C, generics). Clindamycin has been approved in many countries since 1970. Structure and properties Clindamycin (C18H33ClN2O5S, Mr = 425.0 g/mol) is a semisynthetic derivative of lincomycin obtained from (7-chloro-7-deoxy-lincomycin). In the capsules, the active ingredient is present … Clindamycin
Products Norfloxacin is commercially available in the form of film-coated tablets. It was approved in many countries in 1983. The original product, Noroxin, is no longer available, but generics are available. Structure and properties Norfloxacin (C16H18FN3O3, 319.33 g/mol) is a fluoroquinolone. It exists as a white to pale yellow, hygroscopic, photosensitive crystalline powder that is … Norfloxacin
Symptoms Possible symptoms include: Fever Large, blotchy skin rash, skin bleeding. Headache, muscle pain Abdominal pain, nausea, vomiting, lack of appetite. Conjunctivitis Vasculitis, hemorrhage, increased blood clotting, blood circulation disorders, encephalitis, organ failure, necrosis. The disease often leads to severe complications and death. It occurs in the United States, Canada and South America. Cause The … Rocky Mountain Spotted Fever
Products Dequalinium chloride is commercially available in the form of vaginal tablets, which have been approved in many countries since 2002 (Fluomizin). Other dosage forms, such as lozenges, are available for other indications. This article refers to vaginal therapy. Structure and properties Dequalinium chloride (C30H40Cl2N4, Mr = 527.6 g/mol) exists as a yellowish white powder … Dequalinium Chloride