Products Dabigatran is commercially available in capsule form (Pradaxa). It has been approved in many countries since 2012. It was first approved in 2008. Structure and properties Dabigatran (C25H25N7O3, Mr = 471.5 g/mol) is present in drugs as mesilate and in the form of the prodrug dabigatran etexilate, which is metabolized in the organism by … Dabigatran
Products Ranolazine is commercially available in the form of sustained-release tablets (Ranexa). It was approved in the United States as early as 2006, in the EU in July 2008, and in many countries in April 2010. Structure and properties Ranolazine or ()–(2, 6-dimethylphenyl)-4(2-hydroxy-3-(2-methoxyphenoxy)-propyl)-1-piperazine acetamide (C24H33N3O4, Mr = 427.54 g/mol) is a piperazine derivative and a … Ranolazine
Products Micafungin is commercially available as a powder for the preparation of an infusion solution (Mycamine). It was approved in many countries in 2012. Structure and properties Micafungin (C56H70N9NaO23S, Mr = 1292.3 g/mol) is a complex molecule obtained as a derivative of a fermentation product of the fungus F-11899. It is present in the drug … Micafungin
Products Midazolam is commercially available as film-coated tablets and as a solution for injection (Dormicum, generic). It has been approved in many countries since 1982. Midazolam nasal spray has not yet been registered in many countries and must be prepared in a pharmacy as an extemporaneous formulation or imported. In 2012, a solution for use … Midazolam
Products Dexlansoprazole was approved in many countries in 2014 in the form of modified-release capsules (Dexilant). Generic versions were registered in 2020. Structure and properties Dexlansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is the pure -enantiomer of the racetmate lansoprazole (Agopton, both Takeda; generics). It exists as a white crystalline powder that is sparingly soluble in … Dexlansoprazole
Symptoms Pityriasis versicolor is a skin disorder that occurs primarily on areas with high sebum production, such as the back, chest, upper arms, shoulders, armpits, neck, face, and scalp. Round to oval hyper- or hypopigmented patches occur. The skin is slightly thickened, scaly, and sometimes mildly itchy. The patches may be colored, for example, pink, … Pityriasis Versicolor: Medicinal Uses
Symptoms Calf lichen is a localized fungal infection of the skin with vesicles, papules, and pustules. The skin is pale on the inside and surrounded by a red ring on the outside. A strong inflammation is typical. The scalp, face, nails, beard and exposed skin areas such as the arms can be affected. The infection … Calf Lichen
Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin
P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
Microsporum is known as a genus of individual species of fungi that belong to the dermatophytes as well as Fungi imperfecti and are taxonomic representatives of the true tubular fungi. The most important members of the genus include representatives Microsporum audouinii, canis and gypseum species, which live on the skin of animals and humans, as … Microsporum: Infection, Transmission & Diseases
Triazoles are special chemical compounds characterized by a ring-shaped structure. All triazoles always have the chemical molecular formula C2H3N3. This formula indicates that triazoles are composed of five atoms. Each individual molecule consists of two carbon atoms and three nitrogen atoms. What are triazoles? Triazoles are usually aromatic compounds that are heterocyclic and consist of … Triazoles: Effects, Uses & Risks
Trichophyton is the name for a genus of filamentous fungi. This can cause diseases of the skin and hair. What is trichophyton? Various dermatophytes are grouped under the name Trichophyton. They are also part of the Arthrodermataceae family. Trichophytes form a genus of filamentous fungi and belong to the Fungi imperfecti (imperfect fungi). These are … Trichophyton: Infection, Transmission & Diseases
