Products Mifamurtide is commercially available as a powder for a concentrate for the preparation of an infusion dispersion (Mepact). It was approved in the EU in 2009 and in many countries in 2010. It was originally developed in the early 1980s at Ciba-Geigy. Structure and properties Mifamurtide (L-MTP-PE) is a fully synthetic derivative of muramyl … Mifamurtid
Products Salsalat is no longer on sale in many countries. For example, it is available in the USA. Structure and properties Salsalate (C14H10O5, Mr = 258.2 g/mol) is a dimer of salicylic acid. It exists as a white powder that is almost insoluble in water. Effects Salsalate (ATC N02BA06) has anti-inflammatory and analgesic properties. It … Salsalad
Products Ibuprofenarginate is commercially available as film-coated tablets and as granules (Dolo-Spedifen, Spedifen). It has been approved in many countries since 1990. Structure and properties Ibuprofenarginate (C19H32N4O4, Mr = 380.5 g/mol) is the salt of the natural amino acid arginine with the analgesic ibuprofen. Ibuprofen is negatively charged and arginine is positively charged. Ibuprofen is … Ibuprofenarginate
Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone
Products Dexketoprofen is commercially available as film-coated tablets and as a solution for injection (Ketesse). It has been approved in many countries since 2000. In 2017, a fixed combination with tramadol was registered; see Tramadol Dexketoprofen (Skudexa). Structure and properties Dexketoprofen (C16H14O3, Mr = 254.3) is the active -enantiomer of ketoprofen, which exists as a … Dexketoprofen
Products There are no drugs with the active ingredient tolmetin on the market in many countries. Structure and properties Tolmetin (C15H15NO3, Mr = 257.3 g/mol) is a pyrrole and acetic acid derivative. It is present in drugs as tolmetin sodium, which is water soluble. Effects Tolmetin (ATC M01AB03) has analgesic, anti-inflammatory, and antipyretic properties. The … Tolmetin
Products Ibuprofen sodium was commercially available in many countries in the form of film-coated tablets (Saridon /-forte). Meanwhile, Saridon contains ibuprofen rather than the sodium salt (Saridon neo). Structure and properties Ibuprofen sodium (C13H21NaO4, Mr = 264.3 g/mol) is the salt of the analgesic ibuprofen with sodium. It exists as ibuprofen sodium dihydrate (2 H2O). … Ibuprofen Sodium
Products Tepoxaline is commercially available in tablet form (Zubrin). It has been approved in many countries since 2003. Structure and properties Tepoxaline (C20H20ClN3O3, Mr = 385.8 g/mol) is a pyrazole derivative. Effects Tepoxaline (ATCvet QM01AE92) is analgesic and anti-inflammatory. The properties are based on inhibition of prostaglandin synthesis. The effects are mainly mediated by the … Tepoxaline
Diagnosis For diagnosis, we first try to show how long the complaints have been present and especially during which movements they occur. Then the examiner will conduct special tests with the patients to find out which areas of the spine are affected. Various pressure and provocation tests provide the examiner with a quick overview of … Diagnosis | ISG Syndrome
Prophylaxis Due to the unusual and partly also unphysiological weight distribution during pregnancy, increased pulling and stretching movements in the ISG area can always occur. The main weight of the pregnant woman is at the front, automatically the weight is tried to be shifted compensatory to the back, which causes that the joints of the … Prophylaxis | ISG Syndrome
Definition An ISG syndrome is a disease of the so-called sacroiliac joint, which is located between the hip bone and the sacrum. Various causes lead to the fact that the movement in the joint can no longer be carried out without friction, which leads to pain. Cause The causes of ISG syndrome are mainly wedging, … ISG Syndrome
Definition The drug indomethacin belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Indomethacin is mainly used to treat rheumatic diseases. Mode of action of Indometacin Indomethacin inhibits the enzyme cyclooxygenase, which inhibits the formation of prostaglandins: Prostaglandins are substances that play a decisive role in the body in mediating pain, fever and inflammation, among … Indomethacin