Products Zidovudine is commercially available as film-coated tablets, capsules, and syrup (Retrovir AZT, combination products). It was approved in 1987 as the first AIDS drug. Structure and properties Zidovudine (C10H13N5O4, Mr = 267.2 g/mol) or 3-azido-3-deoxythymidine (AZT) is an analog of thymidine. It exists as an odorless, white to beige, crystalline substance that is soluble … Zidovudine (AZT)
Products Azacitidine is commercially available as a lyophilizate for the preparation of a suspension for injection (Vidaza, generic). It has been approved in many countries since 2006. Structure and properties Azacitidine (C8H12N4O5, Mr = 244.2 g/mol) is a derivative of the nucleoside cytidine found in nucleic acids. It belongs to the pyrimidine nucleoside analogues. Azacitidine … Azacitidine
Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19
Products AZD1222 has been in the registration phase in the EU and many countries since the beginning of October 2020 as part of a rolling review and is not yet commercially available. The vaccine was developed at Oxford University’s Jenner Institute, spin-off Vaccitech and AstraZeneca. Efficacy and safety are being evaluated in studies involving up … AZD1222
Products Sofosbuvir is commercially available in the form of film-coated tablets (Sovaldi). It was approved in the United States and EU in 2013 and in many countries in 2014. The very high price of the drug has been a source of debate. Sofosbuvir is also combined fixed with ledipasvir (Harvoni). Cheaper generics are available in … Sofosbuvir
Products Oxygen is commercially available in the form of compressed gas cylinders (oxygen cylinders) with a white color as a compressed gas. In many countries, it is available from PanGas, for example. Structure and properties Oxygen (symbol: O, elemental: O2, atomic number: 8, atomic mass: 15,999) is present as dioxygen (O2, O=O) as a colorless, … Oxygen
Products Carmustine is commercially available in many countries as a powder and solvent for the preparation of an infusion solution (BiCNU). An implant is also available in some countries (Gliadel). Structure and properties Carmustine (C5H9Cl2N3O2, Mr = 214.0 g/mol) belongs to the nitrosoureas. It exists as a yellowish, granular powder that is very sparingly soluble … Carmustine
Structure and properties Lipids are characterized by being soluble in organic (apolar) solvents and generally sparingly soluble or insoluble in water. They have lipophilic (fat-loving, water-repellent) properties. Lipids also exist, with polar structural elements such as the phospholipids or ionized fatty acids. They are called amphiphilic and can form lipid bilayers, liposomes and micelles. For … Lipids
Products Polysaccharides are present as excipients and active ingredients in numerous pharmaceuticals. They play a fundamental role in foods for nutrition. Polysaccharides are also known as glycans (glycans). Structure and properties Polysaccharides are polymeric carbohydrates composed of hundreds to thousands of sugar units (monosaccharides). As few as 11 monosaccharides are referred to as polysaccharides. They … Polysaccharides
Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir
Products Cobalt is found in drugs that contain vitamin B12. Unlike other trace elements, it is otherwise virtually never found in vitamin and mineral supplements. Structure and properties Cobalt (Co) is a chemical element with atomic number 27 that exists as a hard, silver-gray, and ferromagnetic transition metal with a high melting point of 1495 … Cobalt
Products Gemcitabine is commercially available as a lyophilizate for the preparation of an infusion solution (Gemzar, generics). It has been approved in many countries since 1997. Structure and properties Gemcitabine (C9H11F2N3O4, Mr = 263.2 g/mol) is present in drugs as gemcitabine hydrochloride, a white substance that is soluble in water. The pyrimidine gemcitabine is a … Gemcitabine
