pruritus

Itching (Pruritus): Description

Brief overview Treatment: skin care, cotton gloves to prevent scratching while sleeping, airy clothing, cool compresses, relaxation techniques, treatment of the underlying condition. Causes: Allergies, psoriasis, eczema, parasites, kidney and liver diseases, diseases of the blood and lymphatic system, metabolic disorders. Diagnostics: patient interview (anamnesis), physical examination, blood test, smears and tissue samples, imaging procedures … Itching (Pruritus): Description

Peanut Allergy

Symptoms Peanut allergy most commonly affects the skin, digestive tract, and respiratory system. Possible symptoms include: Rhinitis, stuffy nose Itching Hives Skin redness Swelling, angioedema Nausea and vomiting Abdominal cramps Diarrhea Cough, whistling breathing Tightness in the throat, larynxoedema. Voice changes Peanuts are among the food allergens that most commonly cause severe anaphylactic reactions, which … Peanut Allergy

Rivaroxaban

Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban

5-Fluorouracil

Products 5-Fluorouracil is commercially available as an ointment (Efudix), as a topical solution in combination with salicylic acid (Verrumal), and in preparations for parenteral administration. This article refers to topical application. In 2011, 5-fluorouracil at the lower concentration of 0.5% was approved in many countries with Actikerall. Structure and properties 5-Fluorouracil (C4H3FN2O2, Mr = 130.08 … 5-Fluorouracil

Obeticholic Acid

Products Obeticholic acid is commercially available in the form of film-coated tablets (Ocaliva). It has been approved in the EU and US since 2016 and in many countries since 2018. Structure and properties Obeticholic acid (C26H44O4, Mr = 420.6 g/mol) exists as a white powder that is highly soluble in water at a high pH. … Obeticholic Acid

Obiltoxaximab

Products Obiltoxaximab was approved in the United States in 2016 as an infusion product (Anthim). It has not yet been registered in many countries. Obiltoxaximab was developed with funding from national organizations and is intended primarily for the treatment of victims of a terrorist attack with anthrax spores (Strategic National Stockpile). Structure and properties Obiltoxaximab … Obiltoxaximab

Diabetes Mellitus Type 2: Causes and Treatment

Symptoms The possible acute symptoms of type 2 diabetes include: Thirst (polydipsia) and hunger (polyphagia). Increased urination (polyuria). Visual disturbances Weight loss Fatigue, exhaustion, declining performance. Poor wound healing, infectious diseases. Skin lesions, itching Acute complications: Hyperacidity (ketoacidosis), hyperosmolar hyperglycemic syndrome. Untreated diabetes is far from harmless and can lead in the longer term to … Diabetes Mellitus Type 2: Causes and Treatment

Mosquito Bites

Symptoms Possible symptoms after a mosquito bite include local reactions such as: Itching Wheal formation, swelling, induration Redness, feeling of warmth Inflammation Due to the skin lesion, there is a risk of infection. Usually mosquito bites are self-limiting and disappear after a few days on their own. However, a mosquito bite can also cause swelling … Mosquito Bites

Thiazide Diuretics

Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics

Lokivetmab

Products Lokivetmab was approved in the EU in 2017 and in many countries in 2018 in the form of a solution for injection (Cytopoint, Zoetis Belgium SA). Lokivetmab was the first monoclonal antibody to be cleared for animals. In the United States, locivetmab was approved in 2015 (Canine Atopic Dermatitis Immunotherapeutic). Structure and properties Lokivetmab … Lokivetmab

Carbimazole Effects and Side Effects

Products Carbimazole is commercially available in tablet form (Néo-Mercazole). It has been approved in many countries since 1955. Structure and properties Carbimazole (C7H10N2O2S, Mr = 186.23 g/mol) belongs to the group of thioamidthyreostatics, all of which are derivatives of thiourea. Carbimazole is a prodrug that is converted in the body to its active form, thiamazole, … Carbimazole Effects and Side Effects

Perphenazine

Products Perphenazine was commercially available in the form of film-coated tablets (Trilafon). It was approved in many countries in 1957 and went out of commerce on 3/31/2013. Structure and properties Perphenazine (C21H26ClN3OS, Mr = 403.9 g/mol) is a piperidine derivative of phenothiazine. It exists as a white to yellowish white crystalline powder that is practically … Perphenazine