Products Ocriplasmin is commercially available as an injectable (Jetrea). It has been approved in many countries since 2014. Structure and properties Ocriplasmin is a recombinant and truncated derivative of the human proteolytic enzyme plasmin with a molecular weight of 27.2 kDa. It is produced by biotechnological methods. Effects Ocriplasmin (ATC S01XA22) has proteolytic properties on … Ocriplasmin
Effects Reverse transcriptase inhibitors (ATC J05AF) have antiviral properties against HIV. The effects are due to inhibition of the viral enzyme reverse transcriptase, which transcribes viral RNA into DNA and is important for viral replication. Structure and properties Within the drug group, two distinct classes are distinguished. The so-called nucleoside reverse transcriptase inhibitors, abbreviated NRTIs, … Reverse Transcriptase Inhibitors (HIV)
Products Fusidic acid is commercially available as film-coated tablets, cream, ointment, gauze, and ophthalmic drip gel (including Fucidin, Fucithalmic, and generics). It has been approved in many countries since 1968. See also under fusidic acid eye gel. Structure and properties Fusidic acid (C31H48O6, Mr = 516.7 g/mol) belongs to the steroid antibiotics. It is obtained … Fusidic Acid
Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)
Products Dextrans are commercially available in the form of ophthalmic products. Structure and properties Mixture of polysaccharides. Types: Dextran 1, Dextran 40, Dextran 60 for the preparation of parenterals. Effects Dextran (ATC S01XA20) is a natural macromolecular polysaccharide. It forms a persistent film of moisture on the cornea, thereby counteracting the symptoms of mechanical corneal … Dextrane
Products Dextropropoxyphene is no longer on sale in many countries. Depronal retard, Distalgesic, and other drugs are no longer available. According to the French medicines agency AFSSAPS, the active ingredient is also being withdrawn from the market in the EU. Structure and properties Dextropropoxyphene hydrochloride (C22H30ClNO2, Mr = 375.9 g/mol) is a white crystalline powder … Dextropropoxyphene
Products Meloxicam was commercially available in tablet form (Mobicox). It was approved in many countries since 1995. It was discontinued from distribution in 2016. Structure and properties Meloxicam (C14H13N3O4S2, Mr = 351.4 g/mol) belongs to the oxicams and is a thiazole and a benzothiazine derivative. It exists as a yellow powder that is practically insoluble … Meloxicam
Products Abemaciclib was approved in the form of film-coated tablets in the United States in 2017, in the EU in 2018, and in many countries in 2019 (Verzenios). Structure and properties Abemaciclib (C27H32F2N8, Mr = 506.6 g/mol) exists as a white to yellow powder. Effects Abemaciclib (ATC L01XE50) has antitumor and antiproliferative properties. The effects … Abemaciclib
Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine
Products Sidroga women’s tea is no longer available in stores. However, the corresponding mixture can be made in a pharmacy or drugstore. Composition For 100 g: Goose cinquefoil 35.0 g Chamomile flowers 30.0 g Melissa leaves 20.0 g Cardamom fruit 10.0 g Lavender flowers 5.0 g Effects According to the manufacturer, antispasmodic and sedative. Indications … Sidroga Women Tea
Products Potassium bromide is commercially available in Germany in the form of 850 mg tablets (Dibro-Be Mono). In many countries, apart from alternative medicine preparations, no medicines containing potassium bromide are currently available. The drugs can be imported or possibly prepared as an extemporaneous formulation. Kalium bromatum is the Schüssler salt no. 14. Structure and … Potassium Bromide
Products Crotamiton was available in many countries as a cream and lotion for external use (Eurax). It was approved in 1946. In 2012, its distribution was discontinued. Structure and properties Crotamiton (C13H17NO, Mr = 203.3 g/mol) exists as a colorless to pale yellow, oily liquid with a slight amine odor. It is sparingly soluble in … Crotamiton