Amoxicillin (Amoxil)

Products Amoxicillin is commercially available in the form of tablets, film-coated tablets, dispersible tablets, as powder or granules for the preparation of a suspension, as an infusion and injection preparation, and as a veterinary drug. In addition to the original Clamoxyl, numerous generics are available today. Amoxicillin was launched in 1972 and has been approved … Amoxicillin (Amoxil)

Horse Balm

Products The original horse balms are, for example, “Strong Green Ointment ad. us. vet.” or “Green Gel ad. us. vet.” In the past, these veterinary medicines were also used in humans, an application for which they are not approved and which is not without problems. We recommend not to use these veterinary medicines in humans … Horse Balm

Potassium Bromide

Products Potassium bromide is commercially available in Germany in the form of 850 mg tablets (Dibro-Be Mono). In many countries, apart from alternative medicine preparations, no medicines containing potassium bromide are currently available. The drugs can be imported or possibly prepared as an extemporaneous formulation. Kalium bromatum is the Schüssler salt no. 14. Structure and … Potassium Bromide

COX-2 Inhibitor

Products COX-2 inhibitors (coxibe) are commercially available in the form of film-coated tablets and capsules. The first representatives from this group to be approved in many countries were celecoxib (Celebrex, USA: 1998) and rofecoxib (Vioxx, off label) in 1999. At that time, they rapidly developed into blockbuster drugs. However, due to adverse effects, several drugs … COX-2 Inhibitor

Permethrin

Products Permethrin is contained in numerous veterinary medicines, plant protection products, in agents against vermin such as insect sprays against wasps, ants, woodworms, moths, and in repellents. In many countries, only one drug was registered with Swissmedic for a long time, namely Loxazol lotion (1%) against head lice. The cream with 5% permethrin against scabies … Permethrin

Tosyl Chloramide Sodium

Products Tosylchloramide sodium is available in pharmacies as a solution (e.g., chloramine 1%) or as a pure substance. Specialty retailers can order it from Hänseler AG. It is also contained in a few veterinary medicines. A chloramine 1% solution can be prepared as follows: A Tosyl chloramide sodium 1.0 g B Purified water 99.0 g … Tosyl Chloramide Sodium

Kinase Inhibitors

Background Kinases (phosphotransferases) are a large family of enzymes involved in the transduction and amplification of signals on and in cells. They exert their effects by phosphorylating their substrates, that is, by adding a phosphate group to the molecules (Figure). Kinases have complicated names that are usually abbreviated: ALK, AXL, BCR-ABL, c-Kit, c-Met, ERBB, EGFR, … Kinase Inhibitors

Miltefosine

Products Miltefosine is commercially available as an oral solution (milteforan). It is approved exclusively as a veterinary drug in many countries and has been since 2010. In other countries, miltefosine is also used for human use. In Germany, for example, it is available in capsule form (Impavido) for the treatment of leishmaniasis in humans and … Miltefosine

Grapiprant

Products Grapiprant is commercially available in some countries as a veterinary medicine in tablet form for dogs (Galliprant). Structure and properties Grapiprant (C26H29N5O3S, Mr = 491.6 g/mol) Effects Grapiprant (ATCvet QM01AX92) has analgesic and anti-inflammatory properties. The effects are due to selective antagonism at the EP4 receptor and displacement of the natural ligand prostaglandin E2 … Grapiprant

Ivermectin

Products Ivermectin is commercially available in some countries in tablet form (Stromectol). It has not yet been registered in many countries and therefore must be imported from abroad if needed. Ivermectin has been used medicinally since the 1980s, initially primarily as a veterinary drug. This article refers to peroral administration in humans. See also under … Ivermectin

Thymol

Products Thymol, in combination with other essential oils, is found as an ointment, solution, and oil, among other products, mainly in cold remedies (e.g., Vicks VapoRub). As a veterinary medicine, it is available in the form of vaporizing tablets and as a gel. Structure and properties Thymol (C10H14O, Mr = 150.2 g/mol) is present as … Thymol

Lotilan

Products Lotilaner was approved in the EU in 2017 and in the U.S. and many countries in 2018 in chewable tablet form for dogs and as chewable tablets for cats (Credelio). Structure and properties Lotilaners (C20H14Cl3F6N3O3S, Mr = 596.8 g/mol) belongs to the isoxazoline group and exists as a pure -enantiomer. Effects Lotilaner (ATCvet QP53BE04) … Lotilan