Renal Cell Carcinoma (Hypernephroma): Medical History

Medical history (history of illness) represents an important component in the diagnosis of hypernephroma (renal cell carcinoma).

Family history

  • Are there any genetic diseases in your family?
  • Do any people in your family suffer from kidney disease?

Social history

  • What is your profession?
  • Are you exposed to harmful working substances in your profession?

Current medical history/systemic medical history (somatic and psychological complaints).

  • What symptoms/discomforts (e.g., flank pain; swelling in renal bed) have you noticed?
  • How long have these symptoms been present?
  • Have you noticed any blood spotting in the urine?
  • Have you noticed a herniated varicose vein on the left side?
  • Do you feel increased fatigue and tiredness?
  • Do you suffer from nausea?
  • Do you suffer from loss of appetite and/or weight loss?

Vegetative anamnesis incl. nutritional anamnesis.

  • Are you overweight? Please tell us your body weight (in kg) and height (in cm).
  • Do you smoke? If so, how many cigarettes, cigars or pipes per day?

Self history including medication history.

  • Pre-existing conditions (tumor disease)
  • Operations
  • Allergies
  • Medication history

Environmental history

  • Arsenic
    • Men: mortality risk (risk of death)/relative risk (RR) 1.75 (95 percent confidence interval 1.49-2.05).
    • Women: Mortality risk/relative risk 2.09 (95-percent confidence interval 1.69-2.57).
  • Aristolochic acid (constituent of common Easter lucerne; formerly also the main constituent of lady’s gold) – Easter lucerne is a putative medicinal plant that frequently contaminates grain in Balkan regions; The International Agency for Research on Cancer (IARC) classifies aristolochic acid as a carcinogen (cancer-causing agent)
  • Heavy metal contamination, especially lead or cadmium are discussed