Amantadine

Products Amantadine is commercially available as film-coated tablets, capsules, and an infusion solution (Symmetrel, PK-Merz). It has been approved in many countries since 1966. Structure and properties Amantadine (C10H17N, Mr = 151.2 g/mol) is present in drugs as amantadine sulfate or amantadine hydrochloride. Amantadine hydrochloride is a white crystalline powder that is readily soluble in … Amantadine

Olanzapine

Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine

Prednisolone Eye Drops

Products Prednisolone commercially available as an eye drop suspension (Pred forte). Structure and properties Prednisolone is present in the drug in the form of the ester prednisolone acetate (C23H30O6, Mr = 402.5 g/mol). Prednisolone acetate is a prodrug that is hydrolyzed in the body to the active metabolite prednisolone. Effects Prednisolone acetate (ATC S01BA04) has … Prednisolone Eye Drops

Darifenacin

Products Darifenacin is commercially available in the form of sustained-release tablets (Emselex). It has been approved in many countries since 2005. Structure and properties Darifenacin (C28H30N2O2, Mr = 426.6 g/mol) is a tertiary amine. It is present in drugs as darifenacin hydrobromide, a white crystalline powder. Effects Darifenacin (ATC G04BD10) has parasympatholytic properties. It is … Darifenacin

Clotiapine

Products Clotiapine is commercially available in tablet form (Entumin). It has been approved in many countries since 1967. Structure and properties Clotiapine (C18H18ClN3S, Mr = 343.87 g/mol) is a dibenzothiazepine. The structurally closely related neuroleptic quetiapine (Seroquel) also belongs to this group of drugs. Effects Clotiapine (ATC N05AH06) has adrenolytic, antidopaminergic, anticholinergic, antihistamine, sedative, psychomotor … Clotiapine

Clozapine

Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine

Dimenhydrinate

Products Dimenhydrinate is commercially available in the form of tablets, dragées, [chewing gum dragées>chewing gum], and capsules, among others. Since 2012, a combination with the calcium channel blocker cinnarizine has been approved in many countries (Arlevert) see under Cinnarizine and Dimenhydrinate. Structure and properties Dimenhydrinate (C24H28ClN5O3, Mr = 470.0 g/mol) is the salt of diphenhydramine … Dimenhydrinate

Dimetinden Maleate Drops

Products Dimetinden maleate is available as oral drops (Feniallerg drops). They were formerly called Fenistil drops. The drug has been approved in many countries since 1961. Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is … Dimetinden Maleate Drops

Angel Trumpets

Products In many countries, no medicines containing preparations of angel’s trumpet are on the market. Angel’s trumpets are sold as ornamental plants. Stem plant Angel’s trumpets belong to the genus and family Solanaceae. Representatives are, for example , and . The decorative plants are originally from South America. They are perennial shrubs or trees with … Angel Trumpets

Ondansetron

Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron

Ketotifen

Products Ketotifen is commercially available in tablet form and as eye drops (Zaditen, Zabak). It has been approved in many countries since 1977. See also under ketotifen eye drops. Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in … Ketotifen

Ketotifen Eye Drops

Products Ketotifen eye drops have been approved in many countries since 2000 (Zaditen Ophtha / -SDU, Zabak). Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in drugs as ketotifen hydrogen fumarate, a white to brownish yellow crystalline powder … Ketotifen Eye Drops