Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine
Products Dimenhydrinate is commercially available in the form of tablets, dragées, [chewing gum dragées>chewing gum], and capsules, among others. Since 2012, a combination with the calcium channel blocker cinnarizine has been approved in many countries (Arlevert) see under Cinnarizine and Dimenhydrinate. Structure and properties Dimenhydrinate (C24H28ClN5O3, Mr = 470.0 g/mol) is the salt of diphenhydramine … Dimenhydrinate
Products Dimetinden maleate is commercially available as drops, gel, lotion, nasal spray, and nasal drops (Fenistil, Feniallerg, Vibrocil, Otriduo). The nasal products also contain the vasoconstrictor phenylephrine. The Fenistil products used internally (systemically) were renamed Feniallerg in 2009. The capsules and dragées are no longer available. Structure and properties Dimetind (C20H24N2, Mr = 292.4 g/mol) … Dimetindenmaleate
Products Dimetinden maleate has been commercially available in many countries since 1974 in the form of a gel (Fenistil Gel). Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is derived from the two methyl groups … Dimetinden Maleate Gel
Products Dimetinden maleate is available as oral drops (Feniallerg drops). They were formerly called Fenistil drops. The drug has been approved in many countries since 1961. Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is … Dimetinden Maleate Drops
Products Ketotifen is commercially available in tablet form and as eye drops (Zaditen, Zabak). It has been approved in many countries since 1977. See also under ketotifen eye drops. Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in … Ketotifen
Products Ketotifen eye drops have been approved in many countries since 2000 (Zaditen Ophtha / -SDU, Zabak). Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in drugs as ketotifen hydrogen fumarate, a white to brownish yellow crystalline powder … Ketotifen Eye Drops
Products Emedastine is commercially available in the form of eye drops (Emadine). It has been approved in many countries since 1999. Structure and properties Emedastine (C17H26N4O, Mr = 302.41 g/mol) is a benzimidazole and a methyl diazepine derivative. It is present in drugs as emedastinidifumarate, a white powder that is soluble in water. Effects Emedastine … Emedastine
Products Nortriptyline was commercially available in the form of film-coated tablets (nortrilen). It was approved in many countries in 1964. It was discontinued from distribution in 2016. Structure and properties Nortriptyline (C19H21N, Mr = 263.4 g/mol) is present in drugs as nortriptyline hydrochloride, a white powder that is sparingly soluble in water. It is an … Nortriptyline
Products Alcohol is contained in numerous intoxicating and stimulant products, such as wines, sparkling wines, beers and high-proof spirits. Per capita consumption in many countries averages about 8 liters of pure alcohol per year. Ethanol is also available as an open product in various qualities in pharmacies and drugstores (e.g. ethanol 70% with camphor, ethanol … Ethanol
Products Tripelennamine is commercially available as a solution for injection. It is approved exclusively as a veterinary drug in many countries and has been since 1959. In Germany, it is approved for use in humans as a pen to relieve itching after contact with insects, jellyfish, or stinging nettles (Azaron). Structure and properties Tripelennamine (C16H21N3, … Tripelennamine
Products Tricyclic antidepressants are commercially available in many countries in the form of dragées, tablets, capsules, and drops. The first representative, imipramine, was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). Imipramine was approved in many countries in 1958. Structure … Tricyclic Antidepressants
