Products Omega-3 fatty acids are usually administered in the form of softgels. Oils for oral use are also available. Some foods are rich in omega-3 fatty acids (see below). Structure and properties The most important omega-3 fatty acids include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They are polyunsaturated and long-chain fatty acids (PUFA: PolyUnsaturated … Omega 3 Fatty Acids Health Benefits
Products Ketanserin is commercially available as a gel (Vulketan). It has been approved in many countries since 1995 and exclusively as a veterinary drug. In other countries, it is also available for human use as an antihypertensive. Structure and properties Ketanserin (C22H22FN3O3, Mr = 395.4 g/mol) is a quinazolinone derivative. Ketanserin hydrogenotartrate is used in … Ketanserin
Products Felodipine is commercially available in the form of sustained-release tablets. In addition to the original Plendil, generic versions are also available. It has been approved in many countries since 1988. Structure and properties Felodipine (C18H19Cl2NO4, Mr = 384.3 g/mol) is a dihydropyridine. It exists as a white to pale yellow crystalline powder that is … Felodipine
Products Perindopril is commercially available in the form of film-coated tablets and has been approved in many countries since 1989 (Coversum N, generic). It is also approved as a fixed combination with indapamide (Coversum N combi, generic) or amlodipine (Coveram, generic). Generic of the fixed combination with amlodipine was first registered in many countries in … Perindopril
Products Reserpine was commercially available in many countries in the form of dragées as a fixed combination with dihydroergocristin and clopamide (Brinerdin, off label). Structure and properties Reserpine (C33H40N2O9, Mr = 609 g/mol) exists as a crystalline powder or as small, white to faint yellow crystals that slowly darken under the influence of light. The … Reserpine
The active ingredient methyldopa is an amino acid. It is produced synthetically and is used as an antihypertensive. In this context, it is primarily used for the treatment of arterial hypertension. What is methyldopa? The substance methyldopa appears at room temperature as a crystalline solid with virtually no color. The melting point of methyldopa is … Methyldopa: Effects, Uses & Risks
Products Nifedipine is commercially available in the form of sustained-release tablets (generics). It was first approved in the mid-1970s. Sales of the original Adalat were discontinued in many countries in 2019. Structure and properties Nifedipine (C17H18N2O6, Mr = 346.3 g/mol) is a dihydropyridine. It exists as a yellow crystalline powder that is practically insoluble in … Nifedipine: Drug Effects, Side Effects, Dosage and Uses
Products Isradipine is commercially available in capsule form (Lomir SRO). It has been approved in many countries since 1991. Structure and properties Isradipine (C19H21N3O5, Mr = 371.4 g/mol) is a racemate. It exists as a yellow crystalline powder that is practically insoluble in water. Effects Isradipine (ATC C08CA03) has antihypertensive properties. Its effects are due … Isradipine
Products Nebivolol is commercially available in tablet form as a monopreparation (Nebilet, generic, USA: Bystolic) and in combination with hydrochlorothiazide (Nebilet plus). The active ingredient has been approved in many countries since 1998. A fixed combination with valsartan is also available in some countries (Byvalson). Structure and properties Nebivolol (C22H25F2NO4, Mr = 405.4 g/mol) has … Nebivolol
Products Amiloride is sold exclusively in fixed combination with the diuretic hydrochlorothiazide in tablet form. The original Moduretic is no longer available in many countries, but generics are available. Structure and properties Amiloride is present in drugs as amiloride hydrochloride (C6H9Cl2N7O – 2 H2O, Mr = 302.1 g/mol) is present, a pale yellow to greenish … Amiloride
Products Clonidine is commercially available in many countries as tablets and as a solution for injection and has been approved since 1970 (Catapresan). In some countries, clonidine is approved for the treatment of ADHD (eg, Kapvay sustained-release tablets). This article refers to its use in ADHD. Structure and Properties Clonidine (C9H9Cl2N3, Mr = 230.1 g/mol) … Clonidine: Drug Effects, Side Effects, Dosage and Uses
Products Clopamide was commercially available in tablet form and exclusively in combination with other agents (Brinerdin, Viskaldix, off label). Structure and properties Clopamide (C14H20ClN3O3S, Mr = 345.8 g/mol) is a sulfonamide derivative. Effects Clopamide (ATC C03BA03) has diuretic and antihypertensive properties. It promotes excretion of water and sodium by inhibiting reabsorption. Indications In combination preparations: … Clopamide
