Rheumatism is a collective term for all pain and inflammatory diseases of the locomotor system, with partial effects on other systems of our body. Among other things joints, tendons and ligaments, muscles and bones can be affected. The causes are manifold, from autoimmune diseases, metabolic disorders to degeneration (wear and tear in old age). Autoimmune … Physiotherapy for rheumatic diseases
Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment
Products Meloxicam was commercially available in tablet form (Mobicox). It was approved in many countries since 1995. It was discontinued from distribution in 2016. Structure and properties Meloxicam (C14H13N3O4S2, Mr = 351.4 g/mol) belongs to the oxicams and is a thiazole and a benzothiazine derivative. It exists as a yellow powder that is practically insoluble … Meloxicam
Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine
Products Ciclosporin is commercially available as capsules, a drinkable solution, and an infusion concentrate (Sandimmune, Sandimmune Neoral, generics). It has been approved in many countries since 1995. Neoral is the microemulsion formulation that has more stable bioavailability than traditional Sandimmune. In 2016, ciclosporin eye drops were approved (see there). Structure and properties Ciclosporin (C62H111N11O12, Mr … Ciclosporin
Products Etodolac is commercially available as film-coated tablets and sustained-release film-coated tablets (Lodine, Lodine retard). It has been approved in many countries since 1987. Structure and properties Etodolac (C17H21NO3, Mr = 287.4 g/mol) is a racemate. The -enantiomer is pharmacologically more active. Etodolac exists as a white crystalline powder that is practically insoluble in water. … Etodolac
Products Piroxicam is commercially available in tablet form (Felden, generic). It has been approved in many countries since 1986. This article refers to peroral administration. See also under piroxicam gel (off label). Structure and properties Piroxicam (C15H13N3O4S, Mr = 331.4 g/mol) exists as a white to pale yellow crystalline powder that is practically insoluble in … Piroxicam
Products Celecoxib is commercially available in capsule form (Celebrex, generic). It was approved in many countries in 1999 as the first member of the selective COX-2 inhibitors. Generic versions went on sale in 2014. Structure and properties Celecoxib (C17H14F3N3O2S, Mr = 381.37 g/mol) is a benzenesulfonamide and a substituted diaryl pyrazole. It has a V-shaped … Celecoxib
Products Dexamethasone is found in numerous medications. This article refers to peroral administration in the form of tablets (fortecortin, generic). See also the article Cortisone Tablets. Structure and properties Dexamethasone (C22H29FO5, Mr = 392.5 g/mol) exists as a white, crystalline, and odorless powder that is practically insoluble in water. It is a fluorinated and methylated … Dexamethasone: Drug Effects, Side Effects, Dosage and Uses
