Minocycline

Products Minocycline is commercially available in the form of film-coated tablets (Minocin). It has been approved in many countries since 1984. Minac capsules are out of commerce. Topical medicines are additionally available in some countries. Structure and properties Minocylcine (C23H27N3O7, Mr = 457.5 g/mol) is present in drugs as minocycline hydrochloride, a yellow, crystalline, hygroscopic … Minocycline

Enterohepatic Circulation

Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation

Amoxicillin (Amoxil)

Products Amoxicillin is commercially available in the form of tablets, film-coated tablets, dispersible tablets, as powder or granules for the preparation of a suspension, as an infusion and injection preparation, and as a veterinary drug. In addition to the original Clamoxyl, numerous generics are available today. Amoxicillin was launched in 1972 and has been approved … Amoxicillin (Amoxil)

Benzalkonium Chloride Tampons

Products Benzalkonium chloride tampons are approved in many countries (No Gynex). Benzaltex tampons are no longer available. Structure and properties Benzalkonium chloride is a mixture of alkylbenzyldimethylammonium chlorides whose alkyl moiety consists of C8– to C18 chains. It is a white to yellowish white powder or is present as gelatinous, yellowish white, hygroscopic pieces that … Benzalkonium Chloride Tampons

Progestin: Function & Diseases

A progestin is a so-called corpus luteum hormone. Along with estrogens, progestins belong to the female sex hormones, they are so-called steroid hormones. What is progestin? Progestins are so-called steroids, the basic structure of which is pregnane. Progesterone, pregnanediol and pregnenolone are the most important representatives of progestins. The natural progestin is a corpus luteum … Progestin: Function & Diseases

Lymecycline

Products Lymecycline is commercially available in the form of capsules (Tetralysal). It was approved in many countries in 2005. Structure and properties Lymecycline (C29H38N4O10, Mr = 602.6 g/mol) is a water-soluble prodrug of the antibiotic tetracycline with the amino acid lysine. Lymecycline is better absorbed than tetracycline. Effects Lymecycline (ATC J01AA04) has bacteriostatic properties against … Lymecycline

Off-Label Use

Definition In drug therapy, “off-label use” refers to deviations from the officially approved specifications in the drug information leaflet of approved drugs that are ready for use. Frequently, this concerns the areas of application (indications). However, other changes also fall under the definition, for example with regard to the dose, duration of therapy, patient groups, … Off-Label Use

Tablets

Definition and properties Tablets are solid dosage forms containing one or more active pharmaceutical ingredients (exception: placebos). They are intended to be taken by mouth. Tablets may be swallowed unchewed or chewed, dissolved in water or allowed to disintegrate before use, or retained in the oral cavity, depending on the galenic form. The Latin term … Tablets

Vaginal Suppositories

Products Vaginal suppositories are commercially available as drugs and medical devices. Listed below are some active ingredients which are administered vaginally: Estrogens: estriol Progestins: progesterone Antifungals: Econazole, ciclopirox Antiparasitics: Metronidazole, Clindamycin Antiseptics: Povidone–iodine, formerly boric acid. Probiotics: Lactobacilli The egg-shaped vaginal suppositories are also called ovules (singular ovulum). Structure and properties Vaginal suppositories are dosage … Vaginal Suppositories

Prazepam

Products Prazepam is commercially available in tablet form (Demetrin). It has been approved in many countries since 1977. Structure and properties Prazepam (C19H17ClN2O, Mr = 324.8 g/mol) exists as a white crystalline powder that is practically insoluble in water. It carries a cyclopropyl group. Effects Prazepam (ATC N05BA11) has antianxiety, sedative, relaxant, and depressant properties. … Prazepam

Condoms: Effect, Uses & Risks

Condoms are aids to contraception and to avoid transmission of sexually transmitted diseases. The thin rubber sheaths are slipped over the erect penis, preventing sperm from entering the female body. Condoms are among the most popular contraceptives because they are considered relatively safe when used properly. What are condoms? Condoms are thin rubber latex sheaths … Condoms: Effect, Uses & Risks

Androgens: Steroid Hormones

Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones