Contraceptive Ring

Products The progestin etonogestrel and the estrogen ethinylestradiol are commercially available in the form of a vaginal contraceptive ring (NuvaRing). The drug has been approved in many countries since 2003. Generics have also been registered since 2017. Whether the contraceptive ring needs to be stored in the refrigerator depends on the product. Meanwhile, medicines are … Contraceptive Ring

Benzylpenicillin

Products Benzylpenicillin (penicillin G) is commercially available as an injectable (Penicillin Grünenthal). Structure and properties Benzylpenicillin (C16H18N2O4S, Mr = 334.4 g/mol) is present in the drug as benzylpenicillin sodium, a white crystalline powder that is very soluble in water. Other salts are also available. Benzylpenicillin is not acid stable, has low absorption, and therefore can … Benzylpenicillin

St. John’s Wort Health Benefits

Products St. John’s wort and corresponding preparations are commercially available in the form of teas, film-coated tablets, dragées, capsules, and tinctures, among others (e.g., Jarsin, Rebalance, Remotiv, Ceres, Hyperiforce, Hyperiplant, Offenware). Stem plant Common St. John’s wort L. is a perennial plant of the St. John’s wort family, native to Europe and also common in … St. John’s Wort Health Benefits

Hypertension

Symptoms High blood pressure is often asymptomatic, meaning that no symptoms occur. Nonspecific symptoms such as headache, bleeding in the eye, nosebleeds, and dizziness are observed. In advanced disease, various organs such as the vessels, retina, heart, brain and kidney are affected. Hypertension is a known and important risk factor for atherosclerosis, dementia, cardiovascular diseases … Hypertension

Clindamycin

Products Clindamycin is commercially available in several dosage forms. This article refers to oral administration with capsules (Dalacin C, generics). Clindamycin has been approved in many countries since 1970. Structure and properties Clindamycin (C18H33ClN2O5S, Mr = 425.0 g/mol) is a semisynthetic derivative of lincomycin obtained from (7-chloro-7-deoxy-lincomycin). In the capsules, the active ingredient is present … Clindamycin

Nonoxinol 9

Products Nonoxinol 9 is found in or on topical chemical contraceptives such as condoms, diaphragms, suppositories, foams, and creams. Structure and properties Nonoxinol 9 (C33H60O10, Mr = 616.8 g/mol) is a mixture consisting mainly of monononylphenyl ethers of macrogols and having the formula C9H19C6H4-(OCH2-CH2)n-OH, where the average value is for about 9. Nonoxinol 9 may … Nonoxinol 9

Oral Contraceptives

Products Oral contraceptives are commercially available in the form of film-coated tablets and coated tablets. Numerous products with different active ingredients are available from different manufacturers. Structure and properties Oral contraceptives usually contain an estrogen (mainly ethinyl estradiol, sometimes estradiol) and a progestin. Preparations are also available that contain only a progestin (minipill, e.g., desogestrel, … Oral Contraceptives

Progestins

Products Progestogens are commercially available in the form of tablets, capsules, transdermal patches and gels, vaginal rings, injectables, and vaginal preparations, among others. They are contained in hormonal contraceptives, on the one hand in mono- and on the other hand in combination preparations. Structure and properties Progestins are steroid hormones. The lead substance is the … Progestins

Lamotrigine (Lamictal)

Products Lamotrigine is commercially available as tablets and dispersible or chewable tablets (Lamictal, generics). It has been approved in many countries since 1994. Vanillin is typically added to the tablets as a flavoring agent and saccharin as a sweetener. Structure and properties Lamotrigine (C9H7Cl2N5, Mr = 256.1 g/mol) is a chlorinated phenyltriazine derivative that was … Lamotrigine (Lamictal)

Oxytetracycline Eye Ointment

Products No ophthalmic ointments containing oxytetracycline are commercially available in many countries. In Germany, one preparation is available from Jenapharm. Structure and properties Oxytetracycline (C22H24N2O9, Mr = 460.4 g/mol) is present in the ointment as oxytetracycline hydrochloride, a yellow, crystalline, hygroscopic powder that is readily soluble in water. The substance is obtained from certain strains … Oxytetracycline Eye Ointment

Budesonide Capsules

Products Budesonide sustained-release capsules have been approved in many countries since 1998 (Entocort CIR, Budenofalk). Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Effects Budesonide (ATC R03BA02) has anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are … Budesonide Capsules