Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine
Products Buprenorphine is commercially available as sublingual tablets, transdermal patch and injection solution, and depot injection solution (e.g., Temgesic, Transtec, Subutex, generics). It has been approved in many countries since 1979. Structure and properties Buprenorphine (C29H41NO4, Mr = 467.6 g/mol) is present in drugs as buprenorphine hydrochloride, a white crystalline powder that is sparingly soluble … Buprenorphine
Products Various veterinary drugs containing praziquantel are on the market in many countries. In contrast, no human drugs are registered. Human drugs are also available in Germany, the United States, and other countries, such as Biltricide film-coated tablets. Structure and properties Praziquantel (C19H24N2O2, Mr = 312.4 g/mol) is a racemate. It exists as a white … Praziquantel
Products Hemp and preparations made from it, such as marijuana, cannabis resin, THC, and cannabis extracts, are generally among the prohibited narcotics in many countries. However, the Federal Office of Public Health may grant exemptions for research, drug development and limited medical use. In 2013, a cannabis oral spray (Sativex) was approved as a medicine … Cannabis
Products Clonazepam is commercially available as tablets, injectable solution, and oral drops (Rivotril). It has been approved in many countries since 1973. In the United States, it is marketed as Klonopin. Structure and properties Clonazepam (C15H10ClN3O3, Mr = 315.7 g/mol) exists as a faint yellowish crystalline powder that is practically insoluble in water. It is … Clonazepam
Products Telaprevir is commercially available in the form of film-coated tablets (Incivo). It was approved in many countries in 2011. Structure and properties Telaprevir (C36H53N7O6, Mr = 679.8 g/mol) is a peptidomimetic and a ketoamide. It exists as a white crystalline powder that is sparingly soluble in water. Telaprevir is converted in the body to … Telaprevir
Products Nomegestrol acetate is commercially available as a fixed combination with the natural estrogen estradiol in the form of film-coated tablets (Zoely). It has been approved in many countries since 2012 and entered the market in 2013. Structure and properties Nomegestrol acetate (C23H30O4, Mr = 370.5 g/mol) is derived from progestin 19-norprogesterone and progesterone, respectively. … Nomegestrol Acetate
Products Vortioxetine is commercially available as film-coated tablets and as an oral solution (drops). It was approved in the United States and the EU in 2013 and in many countries in 2016 (Brintellix, United States: Trintellix). Structure and properties Vortioxetine (C18H22N2S, Mr = 298.4 g/mol) is a piperazine derivative. It is present in the film-coated … Vortioxetine
Products Two contraceptive patches are currently on the market in many countries. They are transdermal patches: Norelgestromin and ethinyl estradiol (Evra, approved since the year 2003). Gestodene and ethinylestradiol (Lisvy, approved since the year 2015). Unlike the Evra patch (20 cm2), the new Lisvy patch is smaller (11 cm2) and transparent instead of skin-colored. Thus, … Contraceptive Patch
Products The progestin etonogestrel and the estrogen ethinylestradiol are commercially available in the form of a vaginal contraceptive ring (NuvaRing). The drug has been approved in many countries since 2003. Generics have also been registered since 2017. Whether the contraceptive ring needs to be stored in the refrigerator depends on the product. Meanwhile, medicines are … Contraceptive Ring
Products In many countries, the Implanon contraceptive implant with the active ingredient etonogestrel is on the market. It is 4 cm long, 2 mm in diameter, and has been approved since 1999. Structure and properties Etonogestrel (3-keto-desogestrel, C22H28O2, Mr = 324.5 g/mol) is the biologically active metabolite of desogestrel (Cerazette), a progestin derived from 19-nortestosterone. … Contraceptive Sticks
Products Opium tincture is manufactured in pharmacies or ordered from specialized suppliers in pharmacopoeia quality (e.g., Hänseler). As of 2019, it is also approved as a finished drug in many countries (Dropizol, oral drops). Opium and the opioids are subject to narcotics legislation. Opium has been used medicinally for thousands of years. Structure and properties … Opium Tincture
