Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine
Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines
Products Cathinone is not approved as a drug in many countries and is therefore not commercially available. It is one of the banned narcotics (d). In recent years, there have been increasing reports of synthetic cathinone derivatives (designer drugs) such as mephedrone and MDPV, which were initially sold legally as fertilizer and bath salts. Legislation … Cathinon
Products Benproperine is commercially available in the form of tablets (Tussafug). The drug is not registered in many countries. Structure and properties Benproperine (C21H27NO, Mr = 309.4 g/mol) is a piperidine derivative. It is present in the drug as a racemate and benproperine phosphate. Effects Benproperine (ATC R05DB02) has antitussive properties. It is not opioid … Benproperine
Symptoms Rhinitis medicamentosa manifests as a stuffy nose with swollen and histologically altered nasal mucosa. Causes It is the result of prolonged use of decongestant nasal medications (sprays, drops, oils, gels) containing active ingredients such as xylometazoline, oxymetazoline, naphazoline, or phenylephrine. Because the nasal mucosa no longer swells on its own and habituation occurs, the … Rhinitis Medicamentosa
Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine
Products Dexmedetomidine is commercially available as a concentrate for the preparation of an infusion solution (Dexdor). It was approved in many countries in 2012. Structure and properties Dexmedetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative and the -enantiomer of medetomidine. It is structurally closely related to detomidine and is present in drugs as … Dexmedetomidine
Products The fixed combination Deanxit with the two active ingredients melitracene and flupentixol is commercially available in many countries in the form of film-coated tablets. The drug has been approved since 1973, initially as dragées. The marketing authorization holder is the Danish company Lundbeck. Structure and properties The active ingredients are present in the drug … Melitracene and Flupentixol
Products Monk’s pepper extracts are commercially available as film-coated tablets and drops, among others. Stem plant Monk’s pepper L. belongs to the verbenaceae family. The shrub, which grows up to several meters high, is native to the Mediterranean region, Central Asia and India. Monk’s pepper has been used since ancient times to treat women’s ailments. … Monk Pepper
Symptoms The two leading symptoms of Sjögren’s syndrome (pronounced “Schögren”) are dry mouth and dry eyes with associated symptoms such as conjunctivitis, difficulty swallowing and speaking, gingivitis, and tooth decay. The nose, throat, skin, lips and vagina are also frequently dry. In addition, many other organs may be affected less frequently and include muscle and … Sjögren’s Syndrome: Causes and Treatment
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine
