Carmellose

Products Carmellose is commercially available in the form of eye drops and as an oral spray (e.g., Cellufluid, Glandosane, Optava). Structure and properties Carmellose is the calcium or sodium salt of a partially -carboxymethylated cellulose (carboxymethylcellulose calcium or carboxymethylcellulose sodium). Effects Carmellose (ATC S01XA20) forms an optically clear film on the eye, which approximates natural … Carmellose

Cyclobenzaprine

Products Cyclobenzaprine is commercially available in the United States and elsewhere in the form of film-coated tablets. No finished drug products containing cyclobenzaprine are currently registered in many countries. Structure and properties Cyclobenzaprine (C20H21N, Mr = 275.4 g/mol) is present in drugs as cyclobenzaprine hydrochloride, a white crystalline powder that is soluble in water. It … Cyclobenzaprine

Thiethylperazine

Products Thiethylperazine was commercially available in the form of dragées, as a solution for injection, and as suppositories (Torecan, Novartis). It had been approved in many countries since 1960. The suppositories went out of circulation in 2010 due to lack of demand. The other dosage forms were withdrawn from the market in 2014. Structure and … Thiethylperazine

Codeine: Drug Effects, Side Effects, Dosage and Uses

Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses

Promazine

Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine

Promethazine

Products In many countries, drugs containing promethazine are currently no longer on the market. The last product to be withdrawn from the market was Rhinathiol promethazine with the expectorant carbocisteine on January 31, 2009. However, medicines are still available in many countries. The original drug is Phenergan. Promethazine was developed in the 1940s at Rhône-Poulenc, … Promethazine

Propiverine

Products Propiverine was approved in many countries in 2020 in the form of modified-release hard capsules (Mictonorm). Later, coated tablets were also registered (Mictonet). This is an older active ingredient that was available earlier in Germany, for example. Structure and properties Propiverine (C23H29NO3, Mr = 367.5 g/mol) is present in drugs as propiverine hydrochloride. Active … Propiverine

Sedative

Products Sedatives are commercially available in the form of tablets, melting tablets, drops, as injectables and tinctures, among others. Structure and properties Sedatives do not have a uniform chemical structure. Effects The active ingredients have sedative properties. Some are additionally antianxiety, sleep-inducing, antipsychotic, antidepressant, and anticonvulsant. The effects are due to promotion of inhibitory mechanisms … Sedative

Moxonidine

Products Moxonidine is commercially available in tablet form (Physiotens). It has been approved in many countries since 1993. Structure and properties Moxonidine (C9H12ClN5O, Mr = 241.7 g/mol) exists as a white powder that is very sparingly soluble in water. It is an imidazoline derivative structurally related to clonidine. Effects Moxonidine (ATC C02AC05) has central antihypertensive … Moxonidine

Aluminum Lactate

Products Aluminum lactate is commercially available in many countries in combination with lidocaine as an oral spray (Deaftol). Structure and properties Aluminum lactate (C9H15AlO9, Mr = 294.2 g/mol) is the aluminum salt of lactic acid. It consists of the positively charged aluminum ion and three negatively charged lactates (aluminum trilactate). Aluminum lactate exists as a … Aluminum Lactate

Amantadine

Products Amantadine is commercially available as film-coated tablets, capsules, and an infusion solution (Symmetrel, PK-Merz). It has been approved in many countries since 1966. Structure and properties Amantadine (C10H17N, Mr = 151.2 g/mol) is present in drugs as amantadine sulfate or amantadine hydrochloride. Amantadine hydrochloride is a white crystalline powder that is readily soluble in … Amantadine

Inhalation Solution B

Products and ingredients Inhalation solution B is not commercially available as a finished drug in many countries and must be prescribed by a physician as an extemporaneous prescription and prepared in a pharmacy. In practice, different manufacturing prescriptions are used with the pure substances or the solutions. Dospir and Ipramol have a similar composition, but … Inhalation Solution B