Products Nalbuphine is commercially available as a solution for injection (Nalbuphine OrPha). It has been approved in many countries since 2004. Structure and properties Nalbuphine (C21H27NO4, Mr = 357.4 g/mol) is a morphine derivative structurally related to naloxone and oxymorphone. It is present in drugs as nalbuphine hydrochloride. Effects Nalbuphine (ATC N02AF02) has analgesic properties. … Nalbuphin
Products Glatiramer acetate is commercially available as a solution for injection (Copaxone). It has been approved in many countries since 2004. Generic products were registered in 2015. Structure and properties Glatiramer acetate is the acetate salt of a synthetic polypeptide of the four natural amino acids glutamic acid, alanine, tyrosine, and lysine. The average molecular … Glatiramer Acetate
Products Methylnaltrexone is commercially available as a solution for injection (Relistor). It has been approved in many countries since 2009. Structure and properties Methylnaltrexone (C21H26NO4, Mr = 356.4 g/mol) is an -methylated naltrexone. It is present in drugs as methylnaltrexone bromide. Effects Methylnaltrexone (ATC A06AH01) counteracts constipation caused by opioids. The effects are due to … Methylnaltrexone
Products Methylene blue (ATC V03AB17, ATC V04CG05) is commercially available in the form of eye drops (collyre bleu + naphazoline). It has been approved in many countries since 1984. In 2020, a solution for injection was registered as an antidote (methylthioninium chloride Proveblue from Bichsel). Structure and properties Methylene blue or methylthioninium chloride (C16H18ClN3S – … Methylene Blue
Products Methylergometrine is commercially available as a solution for injection (Methergin). Distribution of the drops was discontinued in 2011 and that of the dragées in 2018. Structure and properties Methylergometrine (C20H25N3O2, Mr = 339.4 g/mol) is a semisynthetic derivative of the natural alkaloid ergometrine. It is present in the drug as methyl ergometrine maleate. Effects … Methylergometrine
Products Voretigenneparvovec was approved in the United States in 2017, in the EU in 2018, and in many countries in 2020 as a concentrate and solvent for the preparation of a solution for injection (Luxturna). Structure and properties Voretigenneparvovec is the capsid of an adeno-associated viral vector serotype 2 (AAV2). It contains the cDNA of … Voretigenneparvovec
Products Milrinone is commercially available as a solution for injection (Corotrope, generic). It was approved in many countries in 1992. Structure and properties Milrinone (C12H9N3O, Mr = 211.22 g/mol) is a bipyridine derivative and a carbonitrile derivative of amrinone. Effects Milrinone (ATC C01CE02) has positive inotropic and vasodilatory properties. The effects are due to inhibition … Milrinone
Products Albutrepenone acog alfa was approved in many countries and in the EU in 2016 as a powder and solvent for the preparation of a solution for injection for intravenous use (Idelvion). Structure and properties Albutrepenonacog alfa is a recombinant fusion protein consisting of recombinant blood clotting factor IX combined with recombinant albumin. It is … Albutrepenonacog Alfa
Products Ixekizumab was approved in the United States, the EU, and many countries in 2016 as a solution for injection in a prefilled pen and syringe (Taltz). Structure and properties Ixekizumab is a humanized IgG4 monoclonal antibody with a molecular mass of 146 kDa produced by biotechnological methods. Effects Ixekizumab (ATC L04AC13) has immunosuppressive and … Ixekizumab
Products Nelarabine is commercially available as a solution for injection (Atriance). It has been approved in many countries since 2007. Structure and properties Nelarabine (C11H15N5O5, Mr = 297.3 g/mol) is a purine analog. Effects Nelarabine (ATC L01BB07) has cytotoxic properties. The effects are due to inhibition of DNA synthesis. Indications Treatment of patients with T-cell … Nelarabine
Products Neostigmine is now commercially available in many countries only as a solution for injection (Robinul Neostigmine Injektionslsg). Prostigmine 15 mg tablets are no longer available in many countries. Structure and properties Neostigmine bromide (C12H19BrN2O2, 303.20 g/mol) Effects Neostigmine (ATC N07AA01 , ATC S01EB06) is indirectly parasympathomimetic by inhibiting acetylcholinesterase. It competitively competes with acetylcholine. … Neostigmine
Products Epoetin theta is marketed as a solution for injection (EpoTheta-Teva, in some countries: Eporatio). It was approved in many countries in 2010. Structure and properties Epoetin theta is a recombinant glycoprotein produced by biotechnological methods. It is composed of 165 amino acids and has the same sequence as natural erythropoietin (EPO) produced in the … Epoetin Theta
