Pravastatin

Products Pravastatin is commercially available in tablet form (Selipran, generics). It has been approved in many countries since 1990. Structure and properties Pravastatin (C23H36O7, Mr = 424.5 g/mol) is present in drugs as pravastatin sodium, a white to yellowish-white powder or crystalline powder that is readily soluble in water. It is not a prodrug, unlike … Pravastatin

Hydroxychloroquine

Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine

Fluvoxamine

Products Fluvoxamine is commercially available in the form of film-coated tablets (Floxyfral). It has been approved in many countries since 1983. Structure and properties Fluvoxamine (C15H21F3N2O2, Mr = 318.33 g/mol) is present in drugs as fluvoxamine maleate, a white, odorless, crystalline powder that is sparingly soluble in water. Effects Fluvoxamine (ATC N06AB08) has antidepressant properties. … Fluvoxamine

Torasemide

Products Torasemide is commercially available in tablet form (Torem, generic). It has been approved in many countries since 1993. Structure and properties Torasemide (C16H20N4O3S, Mr = 348.4 g/mol) exists as a white powder that is practically insoluble in water. It is a pyridine-sulfonylurea derivative. Torasemide differs structurally from its precursor furosemide (Lasix, generics), a sulfonamide. … Torasemide

Ciclosporin

Products Ciclosporin is commercially available as capsules, a drinkable solution, and an infusion concentrate (Sandimmune, Sandimmune Neoral, generics). It has been approved in many countries since 1995. Neoral is the microemulsion formulation that has more stable bioavailability than traditional Sandimmune. In 2016, ciclosporin eye drops were approved (see there). Structure and properties Ciclosporin (C62H111N11O12, Mr … Ciclosporin

Droperidol

Products Droperidol is commercially available as a solution for injection (Droperidol Sintetica). It has been approved in many countries since 2006. Structure and properties Droperidol (C22H22FN3O2, Mr = 379.4 g/mol) structurally belongs to the butyrphenones and exists as a white powder that is practically insoluble in water. It is a benzimidazolinone derivative. Effects Droperidol (ATC … Droperidol

Stimulants

Products Stimulants are commercially available as drugs, narcotics, dietary supplements, and foods. Dosage forms include tablets, capsules, and solutions. Structure and properties Stimulants do not have a uniform chemical structure, but groups can be identified. Many, for example the amphetamines, are derived from the natural catecholamines such as epinephrine and norepinephrine. Effects The active ingredients … Stimulants

Fexofenadine

Products Fexofenadine is commercially available in tablet form (Telfast, Telfastin Allergo, generic). It was approved in many countries in 1997 and has been available without a doctor’s prescription since 2010. Telfastin Allergo 120 for self-medication went on sale in February 2011. Fexofenadine is the successor product to terfenadine (Teldane), which had to be withdrawn from … Fexofenadine

Escitalopram

Products Escitalopram is commercially available as film-coated tablets, drops, and meltable tablets (Cipralex, generic). It has been approved in many countries since 2001. Structure and properties Escitalopram (C20H21FN2O, Mr = 324.4 g/mol) is the active -enantiomer of citalopram. It is present in drugs as escitalopram oxalate, a fine, white to slightly yellowish powder that is … Escitalopram

Phytopharmaceuticals

Phytopharmaceuticals – herbal medicinal products. The term phytopharmaceuticals (singular phytopharmacon) is derived from the Greek terms for plant and for drug. In very general terms, then, it refers to herbal medicines. This refers, for example, to dried plant parts, also called medicinal drugs, such as leaves, flowers, barks or roots. These are often prepared as … Phytopharmaceuticals

Venlafaxine: Drug Effects, Side Effects, Dosage and Uses

Products Venlafaxine is commercially available in tablet and sustained-release capsule form. In addition to the original Efexor ER (USA: Effexor XR), generic versions are also available. The active ingredient was approved in many countries in 1997. Structure and properties Venlafaxine (C17H27NO2, Mr= 277.4 g/mol) is a bicyclic phenylethylamine and cyclohexanol derivative that is structurally closely … Venlafaxine: Drug Effects, Side Effects, Dosage and Uses

Fluoxetine: Drug Effects, Side Effects, Dosage and Uses

Products Fluoxetine is commercially available as tablets, dispersible tablets, and capsules (Fluctine, generics, USA: Prozac). It has been approved in many countries since 1991. Structure and properties Fluoxetine (C17H18F3NO, Mr = 309.3 g/mol) is present in the drugs as fluoxetine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a racemate … Fluoxetine: Drug Effects, Side Effects, Dosage and Uses