Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone
Products Dexamethasone is found in numerous medications. This article refers to peroral administration in the form of tablets (fortecortin, generic). See also the article Cortisone Tablets. Structure and properties Dexamethasone (C22H29FO5, Mr = 392.5 g/mol) exists as a white, crystalline, and odorless powder that is practically insoluble in water. It is a fluorinated and methylated … Dexamethasone: Drug Effects, Side Effects, Dosage and Uses
Products Various eye drops containing dexamethasone as suspensions and solutions are commercially available in many countries (Dexafree UD, Maxidex, Spersadex mono, combination products). Structure and properties Dexamethasone (C22H29FO5, Mr = 392.5 g/mol) exists as a white, crystalline, and odorless powder that is practically insoluble in water and is therefore prepared as a suspension. The solutions … Dexamethasone Eye Drops
Products Dermocorticoids are commercially available in the form of creams, ointments, lotions, gels, pastes, foams, scalp applications, shampoos, and solutions, among others. Numerous drugs are available, including many combination preparations. Hydrocortisone was the first active ingredient to be used in the 1950s. Today, dermocorticoids are among the most important drugs in dermatology. Effects Glucocorticoids have … Topical Glucocorticoids: Dermocorticoids
Products Ribavirin is commercially available in the form of film-coated tablets (Copegus). It has been approved in many countries since 1990. Structure and properties Ribavirin (C8H12N4O5, Mr = 244.2 g/mol) is a purine nucleoside analog. It exists as a white crystalline powder that is readily soluble in water. In cells, the drug is biotransformed to … Ribavirin
Products Rifampicin is commercially available as film-coated tablets, coated tablets, capsules, and injectables (Rimactan, generics). In addition to mono, various combination preparations are also available. Rifampicin has been approved in many countries since 1968. This article refers to peroral monotherapy. Structure and properties Rifampicin (C43H58N4O12, Mr = 823 g/mol) exists as a reddish brown to … Rifampicin
Products Clobetasol propionate is commercially available as cream, ointment, foam, shampoo, and scalp application (Dermovate, Clobex, Clarelux). It has been approved in many countries since 1976. Structure and properties Clobetasol propionate (C25H32ClFO5, Mr = 466.97 g/mol) is the ester of clobetasol with propionic acid. It is a derivative of prednisolone. Clobetasol propionate exists as a … Clobetasol Propionate
Products There are no medicines with ricin on the market. What is available is castor oil, but it is free of the toxin because of the manufacturing process. This remains in the remains of the seeds when pressed. Structure and properties Ricin is a natural toxin found in the seeds of the so-called miracle tree … Ricin
Symptoms Possible symptoms include: Fever Large, blotchy skin rash, skin bleeding. Headache, muscle pain Abdominal pain, nausea, vomiting, lack of appetite. Conjunctivitis Vasculitis, hemorrhage, increased blood clotting, blood circulation disorders, encephalitis, organ failure, necrosis. The disease often leads to severe complications and death. It occurs in the United States, Canada and South America. Cause The … Rocky Mountain Spotted Fever
Products Oral budesonide suspension is prepared in pharmacies as an extemporaneous formulation on a physician’s prescription. Corresponding finished drug products are not commercially available. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Preparation To prepare an … Oral Budesonide Suspension
Products Progestogens are commercially available in the form of tablets, capsules, transdermal patches and gels, vaginal rings, injectables, and vaginal preparations, among others. They are contained in hormonal contraceptives, on the one hand in mono- and on the other hand in combination preparations. Structure and properties Progestins are steroid hormones. The lead substance is the … Progestins
Products Nitric oxide is commercially available as a gas for medical use (inhalation gas). It has been approved since 1999. Structure and properties Nitric oxide (NO, Mr = 30.0 g/mol) exists as a colorless gas that turns brown in air. It is a free radical. Nitrogen dioxide forms rapidly in air. Structure: -N=O Effects Nitric … Nitric Oxide
