Products Pegaspargase is commercially available as an injectable (Oncaspar). The drug was approved in the United States in 2006, in the EU in 2016, and in many countries in 2017. Structure and properties Pegaspargase (PEG-L-asparaginase) is the pegylated enzyme L-asparaginase. The PEG units are covalently attached to the enzyme. Effects Pegaspargase (ATC L01XX24) has antileukemic … Pegaspargases
Products The MMR vaccine is commercially available as an injectable. Vaccination has been recommended in many countries since the 1980s. Some preparations also contain the chickenpox vaccine (= MMRV vaccine). Effects MMR (ATC J07BD52) is a live vaccine consisting of attenuated measles, mumps, and rubella viruses. These childhood diseases can cause significant complications and numerous … MMR Vaccination
Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones
Products Rabies vaccine is commercially available as a solution for injection (Rabipur, Rabies Vaccine Mérieux). This article refers to active immunization. Structure and properties The vaccine contains inactivated rabies virus of the Flury LEP or WISTAR PM/WI 38-1503-3M strain. Effects Rabies vaccine (ATC J07BG01) results in the formation of neutralizing antibodies and thus immunity to … Rabies Vaccination (Active Immunization)
Products Deferoxamine is commercially available as an injectable (Desferal). It has been approved in many countries since 1963. Structure and properties Deferoxamine is present in drugs as deferoxamine mesilate (C26H52N6O11S, Mr = 657 g/mol), a white powder that is readily soluble in water. Effects Deferoxamine (ATC V03AC01) forms complexes with trivalent iron and aluminum and … Deferoxamine
Products Amikacin is commercially available as a solution for injection (Amikin). It has been approved in many countries since 1976. Structure and properties Amikacin (C22H43N5O13, Mr = 585.6 g/mol) is semisynthetically prepared from kanamycin A. It is found in drugs as amikacin sulfate, a white powder that is readily soluble in water. Effects Amikacin (ATC … Amikacin
Products Gold compounds are commercially available (worldwide) in the form of capsules and injection solutions (e.g., Ridaura, Tauredon), among others. They are rarely used medicinally today. Structure and properties Elemental gold (Latin: aurum, abbreviation: Au, M. r = 96.97 g/mol, atomic number 79) is a chemical element and a lustrous noble metal with a yellow … Gold
Products Cloprostenol is commercially available as a solution for injection. It has been approved in many countries since 1977 and exclusively as a veterinary drug. Structure and properties Cloprostenol (C22H29ClO6, Mr = 424.9 g/mol) is a synthetic analog of prostaglandin F2α and structurally related to it. It exists as a white powder and is highly … Cloprostenol
Products Tripelennamine is commercially available as a solution for injection. It is approved exclusively as a veterinary drug in many countries and has been since 1959. In Germany, it is approved for use in humans as a pen to relieve itching after contact with insects, jellyfish, or stinging nettles (Azaron). Structure and properties Tripelennamine (C16H21N3, … Tripelennamine
Products Nalbuphine is commercially available as a solution for injection (Nalbuphine OrPha). It has been approved in many countries since 2004. Structure and properties Nalbuphine (C21H27NO4, Mr = 357.4 g/mol) is a morphine derivative structurally related to naloxone and oxymorphone. It is present in drugs as nalbuphine hydrochloride. Effects Nalbuphine (ATC N02AF02) has analgesic properties. … Nalbuphin
Products On the one hand, anabolic steroids are on the market as approved drugs, for example testosterone and other androgens. On the other hand, many agents are also produced and distributed illegally. Structure and properties Anabolic steroids structurally correspond to or are derived from androgens, the male sex hormones. The prototype of the group is … Anabolic Steroids: Synthetic Testosterone
Products Hepatitis A vaccine is commercially available as an injection suspension (Havrix). It has been licensed in many countries since 1993. A fixed combination with hepatitis B vaccine is also available (Twinrix). Structure and properties Hepatitis A vaccine is either hepatitis A virus inactivated with formaldehyde or a liposomal preparation of hepatitis A virus antigen. … Hepatitis A Vaccine
