Products Ergocalciferol (vitamin D2, calciferol) is commercially available in many countries, including as a dietary supplement in the form of capsules. Vitamin D2 is much less commonly used than cholecalciferol (vitamin D3) in many countries. In the United States, on the other hand, ergocalciferol is more traditionally used. Structure and properties Ergocalciferol (C28H44O, Mr = … Ergocalciferol (Vitamin D2)
Products Risperidone is commercially available as film-coated tablets, meltable tablets, an oral solution, and a suspension for intramuscular administration (Risperdal, generics). The active ingredient has been approved in many countries since 1994. Structure and properties Risperidone (C23H27FN4O2, Mr = 410.5 g/mol) exists as a white powder that is practically insoluble in water. It is a … Risperidone: Drug Effects, Side Effects, Dosage and Uses
Products Cefamandol is commercially available as an injectable (Mandokef). It has been approved in many countries since 1978. Structure and properties Cefamandol (C18H18N6O5S2, Mr = 462.5 g/mol) is present in drugs as cefamandolafate, a white powder that is readily soluble in water. Effects Cefamandol (ATC J01DA07) has bactericidal properties. The effects are due to inhibition … Cefamandol
Products Suxamethonium chloride is commercially available as a solution for injection (lysthenone, succinoline). It was introduced in the 1950s and has been approved in many countries since 1954. Suxamethonium chloride is also known as succinylcholine or succinylcholine chloride, especially in English. In jargon, it is also called Suxi or Sux. Structure and properties Suxamethonium chloride … Suxamethonium Chloride
Products Octreotide is commercially available as an injectable (Sandostatin, Sandostatin LAR, generics). It has been approved in many countries since 1988. Structure and properties Octreotide is a synthetic octapeptide derivative of the hormone somatostatin. It is present in the drug as octreotide acetate and has the following structure: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol, xCH3COOH (x = 1.4 to 2.5). … Octreotide
Products In many countries, no drugs containing carfentanil are on the market. The active ingredient is used in veterinary medicine (Wildnil). Legally, it belongs to narcotics. Structure and properties Carfentanil (C24H30N2O3, Mr = 394.5 g/mol) is structurally closely related to fentanyl, being 4-methoxycarbonylfentanyl. Carfentanil citrate is present in pharmaceuticals. The active ingredient was developed at … Carfentanil
Products In many countries, injection solutions containing ferric carboxymaltose (Ferinject, 2007), ferrous sucrose (Venofer, 1949), ferumoxytol (Rienso, 2012), and ferric derisomaltose (ferric isomaltoside, Monofer, 2019) are commercially available. In other countries, other products with different compositions are available, for example, ferrous sodium gluconate. Iron dextrans are rarely used anymore because of the risk for severe … Iron Infusions
Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine
Products No medicines containing clostebol are approved in many countries. Products available in some countries – for example, Italy and Brazil – include Trofodermin cream, a fixed combination with the antibiotic neomycin. Structure and properties Clostebol (C19H27ClO2, Mr = 322.9 g/mol) is a derivative of the male sex hormone testosterone chlorinated at position 4. Trofodermine … Clostebol
Products Dimercaptopropanesulfonic acid is commercially available in some countries as a solution for injection and in capsule form (Dimaval). Structure and properties Dimercaptopropanesulfonic acid or DMPS (C3H8O3S3, Mr = 188.3 g/mol) exists in the drug as a sodium salt and monohydrate. It is a dithiol and a sulfonic acid structurally related to dimercaprol. Effects DMPS … Dimercaptopropanesulfonic Acid (DMPS)
Products Omalizumab is commercially available as a powder and solvent for solution for injection (Xolair). It has been approved in many countries since 2006. Structure and properties Omalizumab is a recombinant, humanized monoclonal antibody with a molecular weight of approximately 149 kDa. Effects Omalizumab (ATC R03DX05) has antiallergic and antiasthmatic properties. The effects are based … Omalizumab
Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses
