Products Albutrepenone acog alfa was approved in many countries and in the EU in 2016 as a powder and solvent for the preparation of a solution for injection for intravenous use (Idelvion). Structure and properties Albutrepenonacog alfa is a recombinant fusion protein consisting of recombinant blood clotting factor IX combined with recombinant albumin. It is … Albutrepenonacog Alfa
Products Nicotinic acid was commercially available in the form of modified-release tablets as a fixed combination with laropiprant (Tredaptive, 1000 mg/20 mg). The combination was approved in many countries in 2009, replacing earlier monopreparations such as Niaspan. The drug was withdrawn from the market on January 31, 2013. Structure and properties Nicotinic acid (C5H5NO2, Mr … Nicotinic Acid
Products Prucalopride is commercially available in the form of film-coated tablets (Resolor). It was approved in many countries and in the EU in 2010. Structure and properties Prucalopride (C18H26ClN3O3, Mr = 367.87 g/mol) is a dihydrobenzofurancarboxamide. It has structural similarities to the prokinetic cisapride (prepulside, out of commerce). Effects Prucalopride (ATC A03AE04) has enterokinetic properties, … Prucalopride
Products Triclabendazole is commercially available as a suspension for animals. It has been approved in many countries since 1986. Structure and properties Triclabendazole (C14H9Cl3N2OS, Mr = 359.7 g/mol) is a chlorinated benzimidazole derivative. Effects Triclabendazole (ATCvet QP52AC01) has antihelmintic properties. Indications Liver fluke infestation (fasciolosis) in sheep, goats, and cattle.
Products Imiquimod is commercially available as a cream in single-use sachets (Aldara 5%). It has been approved in many countries since 1999. Since 2014, a preparation containing 3.75% imiquimod has also been registered in many countries (Zyclara). Structure and properties Imiquimod (C14H16N4, Mr = 240.3 g/mol) is an imidazoquinoline amine structurally similar to nucleoside analogs … Imiquimod: Drug Effects, Side Effects, Dosage and Uses
Products Mirvaso brimonidine gel was approved in the EU in 2013 and in many countries in 2014. Structure and properties Brimonidine (C11H10BrN5, Mr = 292.1 g/mol) is present in the drug as brimonidine tartrate, a white to yellow powder that is soluble in water. It has a similar structure to clonidine and apraclonidine. Effects Brimonidine … Brimonidine Gel
Products Artemether is commercially available as tablets and dispersible tablets as a fixed combination with lumefantrine (Riamet, some countries: Coartem). It has been approved in many countries since 1999. Structure and properties Artemether (C16H26O5, Mr = 298.4 g/mol) is a methyl ether dervate of the sesquiterpene artemisinin from the annual mugwort (, Qing Hao), a … Artemether
Products Naloxone is commercially available as a solution for injection (Naloxone OrPha, Naloxone Actavis) and has been approved in many countries since 2004. Information on combination with oxycodone is presented under the article Oxycodone and Naloxone (Targin, Peroral). As a fixed combination with buprenorphine, naloxone is used to treat opioid dependence (Suboxone, sublingual). In 2014, … Naloxone
