Ergotamine

Products In many countries, drugs containing ergotamine are currently no longer on the market. The active ingredient was available in tablet form in combination with caffeine, among other products (Cafergot), but was withdrawn from the market in 2014. Products containing ergotamine were first launched in the 1920s (Gynergen). Structure and properties Ergotamine (C33H35N5O5, Mr = … Ergotamine

Rizatriptan

Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan

Physiotherapy for migraine

Physiotherapy for migraine is a good supplement or alternative to drug therapy. The aim is to relieve the pain, reduce and alleviate the number of migraine attacks and thus improve the patient’s general quality of life. In the field of physiotherapy, the therapists have various techniques in the areas of relaxation, massage and manual therapy … Physiotherapy for migraine

Retigabine (Ezogabine)

Products Retigabine was approved in many countries as film-coated tablets since 2011 (Trobalt). In the United States, it is referred to as ezogabine. It was discontinued in 2017. Structure Retigabine (C16H18FN3O2, Mr = 303.3 g/mol) is a carbamate that was developed starting from the analgesic flupirtine. The free primary amino group is -glucuronidated (see below). … Retigabine (Ezogabine)

Sumatriptan

Products Sumatriptan is commercially available as film-coated tablets, nasal spray, injectable solution, and suppositories (Imigran, generics). It has been approved in many countries since 1993. Structure and properties Sumatriptan (C14H21N3O2S, Mr = 295.4 g/mol) is present in drugs as sumatriptan or in the form of the salt sumatriptan succinate. Sumatriptan succinate is a white powder … Sumatriptan

Suppositories (Suppositories)

Products Many drugs are available in the form of suppositories. The most commonly administered in the office are acetaminophen suppositories for the treatment of fever and pain in infants and children (photo, click to enlarge). Definition Suppositories are single-dose medicinal preparations with a solid consistency. They usually have an elongated, torpedo-like shape and a smooth … Suppositories (Suppositories)