Products Cefamandol is commercially available as an injectable (Mandokef). It has been approved in many countries since 1978. Structure and properties Cefamandol (C18H18N6O5S2, Mr = 462.5 g/mol) is present in drugs as cefamandolafate, a white powder that is readily soluble in water. Effects Cefamandol (ATC J01DA07) has bactericidal properties. The effects are due to inhibition … Cefamandol
Products Tacrolimus is commercially available in the form of capsules, sustained-release capsules, sustained-release tablets, as a concentrated solution for infusion, as granules, and as an ointment (Prograf, generic, Advagraf, Protopic, generic, Modigraf). It has been approved in many countries since 1996. This article refers to oral use; see also Topical Tacrolimus (Protopic Ointment). Structure and … Tacrolimus (Protopic, Prograf): Drug Effects, Side Effects, Dosage and Uses
Products Methoxyflurane has been approved in many countries since 2018 as a liquid to produce a vapor for inhalation (Penthrox, inhaler). In Australia, the drug has been used since the early 1970s. The active ingredient was originally launched in the 1960s as an anesthetic, but is no longer used as such. Structure and properties Methoxyflurane … Methoxyflurane
Products Hydroquinone is commercially available in many countries as a drug product as a cream (combination preparation). Monopreparations are also available in some countries. Structure and properties Hydroquinone (C6H6O2, Mr = 110.1 g/mol) or 1,4-dihydroxybenzene exists as a white crystalline powder that is very soluble in water. It belongs to the diphenols or dihydroxybenzenes. Effects … Hydroquinone
Products Telavancin is commercially available as a powder for the preparation of a concentrate for infusion solution (Vibativ). It was approved in the EU in 2011. Structure and properties Telavancin (C80H106Cl2N11O27P, Mr = 1755.6 g/mol) is a complex molecule and a semisynthetic derivative of vancomycin. It was supplemented with, among other things, a lipophilic decylaminoethyl … Telavancin
Products Cidofovir was initially marketed in many countries as an infusion concentrate under the brand name Vistide (Gilead). It was approved in many countries in 1997 and had not been available since 2014. In 2017, a concentrate for the preparation of an infusion solution was approved (Sidovis). Structure and properties Cidofovir (C8H14N3O6P, Mr = 279.2 … Cidofovir
Products Kanamycin is marketed in many countries exclusively as a veterinary drug and in combination preparations in the form of a suspension (Kanamastine, Ubrolexin). It has been approved since 1989. In other countries, kanamycin eye drops and ointments are available for human use. Structure and properties Kanamycin is present in drugs as kanamycin monosulfate (C18H38N4O15S … Kanamycin
Products Neomycin is found in several topical medications, including eye drops, eye ointments, ear drops, creams, and ointments. These are usually combination preparations. Neomycin is often combined with bacitracin, as the latter is only effective against gram-positive bacteria. Neomycin was discovered in the 1940s in Selman Waksman’s group at Rutgers University, which identified numerous antibiotics … Neomycin
Products Adefovir is commercially available in tablet form (Hepsera). It has been approved in the United States since 2002, in the EU since 2003, and in many countries since 2004. It was actually originally developed to treat HIV infection, but was not approved for that purpose. Structure and properties Adefovir is present in the drug … Adefovir
Products Cisplatin is available as an infusion concentrate. Several generic products are available in many countries. Platinol is out of commerce. Structure and properties Cisplatin (PtCl2(NH3)2, Mr = 300.1 g/mol) or -diammine dichloroplatinum(II) exists as a yellow powder or as orange-yellow crystals and is sparingly soluble in water. It is an inorganic heavy metal complex … Cisplatin
Products Cefazolin is commercially available as an injection and infusion preparation (Kefzol, generics). It has been approved in many countries since 1974. Structure and properties Cefazolin (C14H14N8O4S3, Mr = 454.5 g/mol) is present in drugs as cefazolin sodium, a white powder that is readily soluble in water. Effects Cefazolin (ATC J01DA04) is bactericidal. Its effects … Cefazolin
