Dimethyl Fumarate

Products Dimethyl fumarate is commercially available in the form of capsules with enteric-coated microtablets (Tecfidera). It has been approved in many countries since 2014. Dimethyl fumarate is also approved for the treatment of psoriasis (Skilarence). This article is related to MS therapy. In 2019, a new prodrug of the active ingredient was approved; see diroximelfumarate … Dimethyl Fumarate

Capsaicin

Products Capsaicin is commercially available in many countries as creams and patches, among other products. Capsaicin cream at 0.025% and 0.075% is not commercially available as a finished drug product. It is produced as a magisterial formulation in pharmacies. See also under the article capsaicin cream. Structure and properties Capsaicin (C18H27NO3, Mr = 305.4 g/mol) … Capsaicin

Hydroxychloroquine

Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine

Calcipotriol

Products Calcipotriol is commercially available as a fixed combination with betamethasone dipropionate as a gel, ointment, and foam (Xamiol, Daivobet, Enstilar, generics). Structure and properties Calcipotriol (C27H40O3, Mr = 412.60 g/mol) is a synthetic derivative of natural vitamin D3 (cholecalciferol). It exists as a white crystalline powder. Effects Calcipotriol (ATC D05AX02) has antiproliferative, anti-inflammatory, and … Calcipotriol

Guselkumab

Products Guselkumab was approved in the United States and the EU in 2017 and in many countries in 2018 as a solution for injection for subcutaneous use (Tremfya). Structure and properties Guselkumab is an IgG1λ monoclonal antibody produced by biotechnological methods. Effects Guselkumab (ATC L04AC16) has anti-inflammatory and immunosuppressive properties. The effects are due to … Guselkumab

Corner of the Mouth Cracks

Symptoms Mouth corner rhagades manifest as inflamed tears in the area of the corners of the mouth. The symptoms are often bilateral and and often involve the adjacent skin. Other symptoms include redness, scaling, pain, itching, crusting and dehydration. Mouth cracks are uncomfortable, bothersome and often slow to heal. Causes Typical causes and risk factors … Corner of the Mouth Cracks

Homeopathy for itching

The occurrence of itching is usually very unpleasant for those affected. It is a general symptom and can be caused by various triggers. Accordingly, the localization of the itching and its severity also differ. Itching is often associated with a strong need to scratch. Many causes are harmless, such as mosquito bites or skin irritation … Homeopathy for itching

Is there a suitable complex agent? | Homeopathy for itching

Is there a suitable complex agent? Active ingredients: The complex agent Cutacalmi® consists of five homeopathic active ingredients. These are: These homeopathic active components are mixed in the same ratio. Effect: The effect of Cutacalmi® is based on a relief of the inflammatory reaction. The complex agent is often used for particularly dry skin and … Is there a suitable complex agent? | Homeopathy for itching

Treatment of the disease only with homeopathy or only as supportive therapy? | Homeopathy for itching

Treatment of the disease only with homeopathy or only as supportive therapy? The treatment of itching depends on its severity and the underlying cause. If the itching is mild or moderate and occurs only occasionally, treatment with homeopathic drugs is a possible option. If there is no improvement within a few days, the treatment should … Treatment of the disease only with homeopathy or only as supportive therapy? | Homeopathy for itching

Cortisone Mixed Ointments

Products Cortisone mixed ointments are not commercially available as finished drug products. They are prepared in pharmacies as extemporaneous preparations. Usually, a cream or ointment containing cortisone is diluted by mixing it with an ingredient-free base, such as Excipial or Antidry. The concentration of the glucocorticoid decreases in the process. However, the risk for adverse … Cortisone Mixed Ointments

Etanercept

Products Etanercept is commercially available as a solution for injection (Enbrel, biosimilars). It has been approved in many countries since 2000. The biosimilars Benepali and Erlezi were approved in many countries in 2018. Structure and properties Etanercept is a dimeric fusion protein composed of the extracellular ligand-binding domain of TNF receptor-2 and the Fc domain … Etanercept