Ofloxacin

Products Ofloxacin is commercially available as eye drops, eye ointment (Floxal, Floxal UD), tablets, and solution for injection (Tarivid). The active ingredient was approved in many countries in 1987, and the ophthalmic agents in 1992. The enantiomer levofloxacin is also on the market (Tavanic, generics). This article refers to ocular use. Structure and properties Ofloxacin … Ofloxacin

Ofatumumab

Products Ofatumumab was approved in 2009 as a concentrate for the preparation of an infusion solution for leukemia treatment (Arzerra). In 2020, a solution for injection was approved in the United States for MS treatment (Kesimpta). Structure and properties Ofatumumab is a human IgG1 monoclonal antibody produced by biotechnological methods. It has a molecular mass … Ofatumumab

Olanzapine

Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine

Omalizumab

Products Omalizumab is commercially available as a powder and solvent for solution for injection (Xolair). It has been approved in many countries since 2006. Structure and properties Omalizumab is a recombinant, humanized monoclonal antibody with a molecular weight of approximately 149 kDa. Effects Omalizumab (ATC R03DX05) has antiallergic and antiasthmatic properties. The effects are based … Omalizumab

Ketoprofen

Products Ketoprofen is commercially available as a gel (Fastum). It has been approved in many countries since 1992 and in the EU since 1978. The -enantiomer dexketoprofen is available as tablets and as a solution for injection (Ketesse). This article refers to external use. After the safety of topical ketoprofen was questioned in France in … Ketoprofen

Emicizumab

Products Emicizumab was approved in the United States in 2017 and in the EU and many countries in 2018 as a subcutaneous solution for injection (Hemlibra). Structure and properties Emicizumab is a humanized and modified bispecific IgG4 monoclonal antibody that binds Factor IXa and Factor X. It is a human antibody. It has a molecular … Emicizumab

Clonazepam

Products Clonazepam is commercially available as tablets, injectable solution, and oral drops (Rivotril). It has been approved in many countries since 1973. In the United States, it is marketed as Klonopin. Structure and properties Clonazepam (C15H10ClN3O3, Mr = 315.7 g/mol) exists as a faint yellowish crystalline powder that is practically insoluble in water. It is … Clonazepam

Sildenafil

Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil

Hexoprenaline

Products Hexoprenaline is commercially available as a solution for injection (Gynipral). It has been approved in many countries since 1984. Approval for the tablets was revoked on Dec. 31, 2013. This due to the potential cardiovascular side effects that may occur in the mother and child. Structure and properties Hexoprenaline (C22H32N2O6, Mr = 420.5 g/mol) … Hexoprenaline

Mesna

Products Mesna is commercially available as film-coated tablets and as a solution for injection (Uromitexan). It has been approved in many countries since 1981. Structure and properties Mesna (C 2 H 5 NaO 3 S 2 , M r = 164.2 g/mol) is a thiol compound. It exists as a white to pale yellow, crystalline, … Mesna

Vonicog Alfa

Products Vonicog alfa was approved in the United States in 2015 and in the EU and Switzerland in 2018 as a lyophilizate and solvent for the preparation of a solution for injection (Veyvondi, USA: Vonvendi). It was the first recombinant von Willebrand factor. Structure and properties Vonicog alfa is a purified, recombinant, human von Willebrand … Vonicog Alfa