Products Labetalol is commercially available in tablet form and as a solution for injection (Trandate). It has been approved in many countries since 1978. Structure and properties Labetalol (C19H24N2 O3, Mr = 328.4 g/mol) is present in drugs as labetalol hydrochloride, a white powder that is sparingly soluble in water. Effects Labetalol (ATC C07AG01) has … Labetalol
Products Regadenoson is commercially available as a solution for injection (Rapiscan). It was approved in the United States in 2008, in the EU in 2010, and in many countries in 2017. Structure and properties Regadenoson (C15H18N8O5, Mr = 390.4 g/mol) is present in the drug as a monohydrate. It is a derivative of adenosine. Effects … Regadenoson
Products Haloperidol is commercially available as tablets, drops (Haldol), and as a solution for injection (Haldol, Haldol decanoas). It has been approved in many countries since 1960. Structure and properties Haloperidol (C21H23ClFNO2, Mr = 375.9 g/mol) is a derivative of pethidine, which is itself derived from atropine. It has structural similarity to loperamide. Haloperidol exists … Haloperidol
Products Epoetin alfa is commercially available as a solution for injection (Eprex, Binocrit, Abseamed). It has been approved in many countries since 1988. Structure and properties Epoetin alfa is a recombinant glycoprotein with a molecular mass of approximately 30 kDa produced by biotechnological methods. It is composed of 165 amino acids and has the same … Epoetin Alfa
Products Phytomenadione is commercially available as a solution for injection and a solution for oral use (Konakion MM). It has been approved in many countries since 1987. Structure and properties Phytomenadione (C31H46O2, Mr = 450.7 g/mol) is a mixture of -phytomenadione, -phytomenadione, and -epoxyphytomenadione. It exists as a clear, intense yellow, viscous, oily liquid and … Phytomenadione
Products Tobramycin is commercially available as a solution for injection, solution for inhalation, and in the form of eye drops, eye gel, and eye ointment. This article refers to the solution for injection (Obracin), which has been approved in many countries since 1974. See also tobramycin inhalation and tobramycin eye drops. Structure and properties Tobramycin … Tobramycin
Products Urapidil is commercially available as a solution for injection (Ebrantil). It has been approved in many countries since 1983. Structure and properties Urapidil (C20H29N5O3, Mr = 387.5 g/mol) is a derivative of uracil and piperazine. It is present in drugs as urapidil hydrochloride. Effects Urapidil (ATC C02CA06) has antihypertensive and sympatholytic properties. It lowers … Urapidil
Products Romosozumab was approved for injection in the United States and EU in 2019 and in many countries in 2020 (Evenity). Structure and properties Romosozumab is a humanized Ig2 monoclonal antibody with a molecular mass of 149 kDa produced by biotechnological methods. Effects Romosozumab (ATC M05BX06) promotes bone formation and, to a lesser extent, additionally … Romosozumab
Products Bortezomib is commercially available as a lyophilizate for the preparation of a solution for injection (Velcade). It has been approved in many countries since 2005. Generic versions were registered in 2018. Structure and properties Bortezomib (C19H25BN4O4, Mr = 384.2 g/mol) is a dipeptidyl derivative of boric acid. Effects Bortezomib (ATC L01XX32) has cytotoxic and … Bortezomib
Products Amiodarone is commercially available in tablet form and as a solution for injection (Cordarone, generics). It has been approved in many countries since 1968. Structure and properties Amiodarone (C25H29I2NO3, Mr = 645.3 g/mol) is an iodinated benzofuran derivative derived from khellin. It is present in drugs as amiodarone hydrochloride, a white, fine, crystalline powder … Amiodarone (Nexterone) for Arrhythmia
Products Ranibizumab is commercially available as a solution for injection (Lucentis). The drug was approved in the United States and many countries in 2006 and in the EU in 2007. The drug’s high price is controversial, especially when compared with bevacizumab (Avastin), which is structurally and pharmacologically similar. Bevacizumab is not approved for these indications … Ranibizumab
Products Metoclopramide is commercially available in tablet, solution, and solution for injection (Primpéran, Paspertin). It has been approved in many countries since 1967. The drops and suppositories for children were withdrawn from the market in November 2011 because of the risk for extrapyramidal side effects. Structure and properties Metoclopramide (C14H22ClN3O2, Mr = 299.8 g/mol) is … Metoclopramide
