Glimepiride

Products Glimepiride is commercially available in tablet form (Amaryl, generic). It has been approved in many countries since 1995. Structure and properties Glimepiride (C24H34N4O5S, Mr = 490.62 g/mol) exists as a white to yellowish-white, crystalline and odorless powder that is practically insoluble in water. It belongs structurally to the sulfonylureas. Effects Glimepiride (ATC A10BB12) has … Glimepiride

Bromelain Effects and Side Effects

Products Bromelain was commercially available in many countries in the form of dragées (Traumanase), and dietary supplements containing pineapple powder are available. Other drugs are approved abroad, for example, Wobenzym and Phlogenzym. Wobenzym is registered in many countries only in the canton of Appenzell Ausserrhoden. Structure and properties Bromelain is the name given to a … Bromelain Effects and Side Effects

Brinzolamide

Products Brinzolamide is form of eye drops commercially available (Azopt) and approved in many countries since 1991. Generic versions were released in 2015. Brinzolamide has also been available in a fixed combination with timolol since 2009 (Azarga). In 2015, a fixed combination with brimonidine was approved; see brinzolamide brimonidine (Simbrinza). Structure and properties Brinzolamide (C12H21N3O5S3, … Brinzolamide

Trimethoprim and Sulfamethoxazole

Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole

Silver Sulfadiazine

Products Silver sulfadiazine is commercially available as creams and gauzes (Flammazine, Ialugen Plus with hyaluronic acid to promote wound healing). It has been approved in many countries since 1974. Structure and properties Sulfadiazine (C10H10N4O2S, Mr = 250.3 g/mol) exists as in the form of crystals or as a crystalline powder with white, yellowish or light … Silver Sulfadiazine

Antibiotic Eye Drops to treat Bacterial Eye Infections

Products Eye drops containing antibiotics are available from various manufacturers in pharmacies. They are also combined with other active ingredients such as glucocorticoids fix. Structure and properties The drops contain antibiotics from different chemical groups (see below). Effects Depending on the active ingredient, the antibiotics have bacteriostatic to bactericidal properties, meaning they inhibit the growth … Antibiotic Eye Drops to treat Bacterial Eye Infections

Methionine

Products Methionine is commercially available in the form of tablets. Acimethine film-coated tablets, which require a prescription, were approved as a drug in 1988. Burgerstein L-Methionine is a dietary supplement with no indication. Structure and properties L-methionine (C7H13NO3S, Mr = 191.2 g/mol) is a natural, sulfur-containing, and essential amino acid used in the body for, … Methionine

Methotrexate Ready-To-Use Syringe

Products Prefilled methotrexate syringes have been approved in many countries since 2005 (Metoject, generic). They contain between 7.5 to 30 mg of active ingredient, in increments of 2.5 mg. The dose is much lower than for chemotherapy (“low-dose methotrexate“). The syringes are stored at room temperature between 15 to 25 °C and protected from light. … Methotrexate Ready-To-Use Syringe

Mercaptopurine

Poducts Mercaptopurine is commercially available in tablet and oral suspension form (Puri-Nethol, Xaluprine). The active ingredient has been approved in many countries since 1955. Structure and properties Mercaptopurine (C5H4N4S – H2O, Mr = 170.2 g/mol) exists as a yellow crystalline powder that is practically insoluble in water. It is an analog of the purine bases … Mercaptopurine

Cidofovir

Products Cidofovir was initially marketed in many countries as an infusion concentrate under the brand name Vistide (Gilead). It was approved in many countries in 1997 and had not been available since 2014. In 2017, a concentrate for the preparation of an infusion solution was approved (Sidovis). Structure and properties Cidofovir (C8H14N3O6P, Mr = 279.2 … Cidofovir

Xipamide

Products Xipamide is not currently registered or commercially available in many countries. In Germany and Austria, it is available in tablet form (Aquaphor, Aquaphoril, generics). Structure and properties Xipamide (C15H15ClN2O4S, Mr = 354.8 g/mol) has a sulfonamide structure and is structurally related to the thiazides, but acts from the blood side. It exists as a … Xipamide

Stevens-Johnson syndrome

What is Stevens-Johnson syndrome? Stevens-Johnson syndrome is a very rare and serious disease. The cause of this disease is often a previous infection or the intake of a new drug. The disease is caused by an overreaction of the immune system. The disease becomes noticeable by a detachment of the skin, painful blisters and a … Stevens-Johnson syndrome