Products In many countries, kava is currently only available in the form of highly diluted homeopathic medicines. For example, Similasan Kava-Kava tablets contain kava in the homeopathic potencies D12, D15 and D30. This remedy no longer contains kava. Mother tinctures and low potencies up to and including D6 may no longer be sold. Previously distributed … Kava
Products Azacitidine is commercially available as a lyophilizate for the preparation of a suspension for injection (Vidaza, generic). It has been approved in many countries since 2006. Structure and properties Azacitidine (C8H12N4O5, Mr = 244.2 g/mol) is a derivative of the nucleoside cytidine found in nucleic acids. It belongs to the pyrimidine nucleoside analogues. Azacitidine … Azacitidine
Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval
Products Bisphosphonates are commercially available in the form of film-coated tablets and as injection and infusion preparations. They are also combined fixed with vitamin D3. Their effects on bone were described in the 1960s. Etidronate was the first active ingredient to be approved (out of trade). Structure and properties Bisphosphonates contain a central carbon atom … Bisphosphonates Effects and Side Effects
Products Eucalyptus oil capsules have been approved in many countries since 2016 (Sibrovita N). In Germany, they have been on the market since the 1990s (Aspecton Eukaps). Structure and properties Eucalyptus oil is an essential oil obtained by steam distillation and subsequent rectification from the fresh leaves or branch tips of various 1,8-cineole-rich eucalyptus species. … Eucalyptus Oil Capsules
Products Ezetimibe is commercially available in tablet form, as a monopreparation (Ezetrol, generic), and as a fixed combination with simvastatin (Inegy, generic) and with atorvastatin (Atozet). Also released is a combination with rosuvastatin. Ezetimibe was approved in many countries and in the United States in 2002. Generic and auto-generics entered the market in November 2017. … Ezetimibe
Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans
Products Satralizumab was approved in many countries in 2020 as a solution for injection (Enspryng). Structure and properties Satralizumab is a humanized IgG2 monoclonal antibody produced by biotechnological methods. Effects Satralizumab (ATC L04AC19) has anti-inflammatory and immunosuppressive properties. The effects are due to binding to the soluble and membrane-bound human IL-6 receptor (IL-6R), preventing signal … Satralizumab
Products Carmustine is commercially available in many countries as a powder and solvent for the preparation of an infusion solution (BiCNU). An implant is also available in some countries (Gliadel). Structure and properties Carmustine (C5H9Cl2N3O2, Mr = 214.0 g/mol) belongs to the nitrosoureas. It exists as a yellowish, granular powder that is very sparingly soluble … Carmustine
Products Carvedilol is commercially available in tablet form (Dilatrend, generic). It has been approved in many countries since 1995. Carvedilol is also combined with ivabradine fixed (Carivalan). Structure and properties Carvedilol (C24H26N2O4, Mr = 406.5 g/mol) is a racemate, with both enantiomers participating in the pharmacological effects. It exists as a white crystalline powder that … Carvedilol
Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens
Products Sedatives are commercially available in the form of tablets, melting tablets, drops, as injectables and tinctures, among others. Structure and properties Sedatives do not have a uniform chemical structure. Effects The active ingredients have sedative properties. Some are additionally antianxiety, sleep-inducing, antipsychotic, antidepressant, and anticonvulsant. The effects are due to promotion of inhibitory mechanisms … Sedative
