Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Propylene Glycol

Products As a pure substance, propylene glycol is available in pharmacies and drugstores, among other places. It is contained in many medicines, medical devices and cosmetics, for example in gels, creams, preparations for inhalation, injectables and film-coated tablets. Structure and properties Propylene glycol or propane-1,2-diol (C3H8O2, Mr = 76.1 g/mol) is a racemate. It exists … Propylene Glycol

Valerian Effects and Side Effects

Products Valerian is usually taken in the form of valerian drops (alcoholic tincture), film-coated tablets or dragées. Other dosage forms are available, such as valerian juice, capsules, powders, baths, mother tinctures, and teas. Valerian is often combined with other sedative medicinal plants, especially hops. Among the best-known products in many countries are, for example, the … Valerian Effects and Side Effects

Morning-After Pill for Contraception

Products The so-called “morning-after pill” is commercially available in many countries in the form of tablets and film-coated tablets. It is also available in pharmacies under medical treatment or after a structured consultation with dispensing documentation. An alternative is the copper IUD (“morning-after coil”). The name “pill” is not correct from a pharmaceutical point of … Morning-After Pill for Contraception

Cefpodoxime

Products Cefpodoxime is commercially available as film-coated tablets and as granules for preparation of a suspension (Podomexef, generics). It has been approved in many countries since 1991. Structure and properties Cefpodoxime (C15H17N5O6S2, Mr = 427.5 g/mol) is present in drugs as cefpodoxime proxetil. It is an ester prodrug and is rapidly converted to cefpodoxime in … Cefpodoxime

Hawthorn: Medicinal Uses

Products Hawthorn is commercially available in the form of film-coated tablets, capsules, as drops, and as a tea, among others (e.g., Zeller Herz, Cardiplant, Sidroga Weissdorn, Vogel Crataegisan). Scientifically well documented are standardized extracts such as WS 1442. Stem plant Hawthorn, of the rose family, is a thorny shrub or small tree native to Europe. … Hawthorn: Medicinal Uses

Dydrogesterone

Products Dydrogesterone is commercially available in the form of film-coated tablets (Duphaston, fixed combination with estradiol: Femoston conti). It has been approved in many countries since 1963. Structure and properties Dydrogesterone (C21H28O2, Mr = 312.4 g/mol) Effects Dydrogesterone (ATC G03DB01) has gestagenic properties. Indications Hormone replacement therapy in combination with an estrogen (menopause, ovariectomy). Cycle … Dydrogesterone

Spironolactone

Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone

Midazolam

Products Midazolam is commercially available as film-coated tablets and as a solution for injection (Dormicum, generic). It has been approved in many countries since 1982. Midazolam nasal spray has not yet been registered in many countries and must be prepared in a pharmacy as an extemporaneous formulation or imported. In 2012, a solution for use … Midazolam

Selexipag

Products Selexipag was approved in the United States in 2015 and in the EU and many countries in 2016 in film-coated tablet form (Uptravi). Structure and properties Selexipag (C26H32N4O4S, Mr = 496.6 g/mol) is a diphenylpyrazine derivative. It is biotransformed in the liver by carboxylesterase 1 (CES1) to the active metabolite ACT-333679 (MRE-269). The metabolite … Selexipag

St. John’s Wort Health Benefits

Products St. John’s wort and corresponding preparations are commercially available in the form of teas, film-coated tablets, dragées, capsules, and tinctures, among others (e.g., Jarsin, Rebalance, Remotiv, Ceres, Hyperiforce, Hyperiplant, Offenware). Stem plant Common St. John’s wort L. is a perennial plant of the St. John’s wort family, native to Europe and also common in … St. John’s Wort Health Benefits

Hypromellose (Hydroxypropylmethylcellulose)

Products Hypromellose is commercially available in tear substitutes in the form of eye drops. It is also present in tablets as a pharmaceutical [excipient>]. Structure and properties Hypromellose (methylhydroxypropyl cellulose) is a partially -methylated and -(2-hydroxypropylated) cellulose. It exists as a white, yellowish white or grayish white powder or as granules and is practically insoluble … Hypromellose (Hydroxypropylmethylcellulose)