Side effects The most important side effects of the macrolides are the effects on the liver. Therapy with macrolides can lead to damage of liver cells. The higher the dose of the active substance, the more likely it is that this damage will occur. This is mainly due to the fact that the macrolides are … Side effects | Macrolides
Symptoms Rosacea is a chronic inflammatory skin disorder of the face that typically affects the cheeks, nose, chin, and central forehead symmetrically (Figure). The skin around the eyes is left out. It occurs more often in people with fair skin and in middle age, but it can occur in any skin type and at any … Rosacea Causes and Treatment
Products Roxithromycin was commercially available in tablet form (Rulid). It is no longer available in many countries. Effects Roxithromycin is (ATC J01FA06) bacteriostatic. It inhibits bacterial protein synthesis; see under macrolides. Indications Bacterial infectious diseases
Products Tildipirosin is commercially available as a solution for injection. The drug was approved in many countries in 2013. Structure and properties Tildipirosin (C41H71N3O8, Mr = 734.0 g/mol) is a 16-membered semisynthetic macrolide antibiotic. Effects Tildipirosin (ATCvet QJ01FA96) has bacteriostatic to bactericidal properties. The effects are due to inhibition of protein synthesis by binding to … Tildipirosin
Products Domperidone is commercially available as film-coated tablets, lingual tablets, and as a suspension (Motilium, generics). It was synthesized in 1974 and has been approved in many countries since 1979. Structure and properties Domperidone (C22H24ClN5O2, Mr = 425.9 g/mol) exists as a white powder that is practically insoluble in water. It is a benzimidazole derivative … Domperidone
Products Mizolastine was commercially available in tablet form (Mizollen, 10 mg) and approved in many countries since 1996. The tablets are no longer available today. For example, fexofenadine (Telfast) or another 2nd-generation antihistamine can be used as an alternative. Structure and properties Mizolastine (C24H25FN6O, Mr = 432.5 g/mol) a piperidine and benzimidazole derivative. It is … Mizolastine
Symptoms Erysipelas manifests as a painful, hyperthermic, clearly demarcated, shiny, and flaming redness of the skin with swelling. In addition to local reactions, flu-like general symptoms such as fever, chills, nausea, and poor general condition occur. The lymphatic channels are inflamed, the lymph nodes swell and hurt. Young and old people are most affected. Typically, … Erysipelas Skin Infection: Symptoms, Causes, Treatment
Symptoms Erysipeloid usually occurs on the back of the hand and fingers and manifests as an intensely inflamed red-purple skin redness with a clear and slightly raised border. It spreads in a ring-like pattern. The hands may swell severely. Blisters and erosions may occur, and mild itching and pain sometimes accompany the infection. However, general … Erysipeloid
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Symptoms Cholera manifests as severe, watery, milky-white diarrhea (“rice water“) that leads to a large loss of fluids and electrolytes and dehydration and dehydration within hours. Other possible symptoms include nausea and vomiting. The massive fluid loss can lead to shock, renal failure, convulsions, coma and, if left untreated, death in up to half of … Cholera Causes and Treatment
Symptoms Legionellosis manifests itself in the following symptoms: Cough, shortness of breath Severe pneumonia High fever, chills Muscle pain, aching limbs Headache Legionellosis can lead to severe complications such as respiratory failure and death. Mortality is relatively high. Pontiac fever is a mild infection with Legionella, which lasts only about a week and runs without … Legionellosis
Products Gamithromycin is commercially available as a solution for injection. It has been approved in many countries since 2010. Structure and properties Gamithromycin (C40H76N2O12, Mr = 777.0 g/mol) Effects Gamithromycin (ATCvet QJ01FA95) has bacteriostatic to bactericidal properties…. Indications For therapy and metaphylaxis of respiratory disease in cattle caused by , and .
