Products Pyriproxifen is commercially available as a spot-on solution for cats. Medicines for dogs are approved in many countries but are not currently available. Structure and properties Pyriproxifen (C20H19NO3, Mr = 321.4 g/mol) is a pyridine derivative derived from fenoxycarb. Effects Pyriproxifen (ATCvet QP53AX23) inhibits the development of flea eggs and larvae for 3 months … Pyriproxifen
Products Nifurpirinol is commercially available in tablet form. It has been approved in many countries since 2003. Structure and properties Nifurpirinol (C12H10N2O4, Mr = 246.2 g/mol) is a nitrated furan and pyridine derivative. Effects Nifurpirinol (ATCvet QJ01XE) has antibacterial properties. Indications In ornamental fish in ponds or freshwater and saltwater aquariums to treat bacterial infections.
Products Amifampridine is commercially available in tablet form (Firdapse). It has been approved in many countries since 2012. Structure and properties Amifampridine (C5H7N3, Mr = 109.1 g/mol) is present in drugs as amifampridine phosphate. It is the pyridine derivative 3,4-diaminopyridine. Amifampridine is structurally closely related to fampridine (4-aminopyridine), which is also commercially available. Effects Amifampridine … Amifampridine
Products Lemborexant was approved in the United States in 2019 in film-coated tablet form (Dayvigo). This as the second agent in the orexin receptor antagonist group. Structure and properties Lemborexant (C22H20F2N4O2, Mr = 410.42 g/mol) is a pyrimidine and pyridine derivative. It exists as a white powder and is practically insoluble in water. Effects Lemborexant … Lemborexant
Products Nicotine is commercially available in the form of chewing gum, lozenges, sublingual tablets, transdermal patch, oral spray, and inhaler (Nicorette, Nicotinell, generics). The first nicotine replacement product was approved in many countries in 1978. Structure and properties Nicotine (C10H14N2, Mr = 162.2 g/mol) exists as a colorless to brownish, viscous, hygroscopic, volatile liquid that … Nicotine: Drug Effects, Side Effects, Dosage and Uses
Products Nitenpyram is commercially available in tablet form (Capstar). It has been approved in many countries since 1999. Structure and properties Nitenpyram (C11H15ClN4O2, Mr = 270.7 g/mol) is a chlorinated pyridine derivative derived from nicotine. It is structurally related to imidacloprid. Effects Nitenpyram (ATCvet QP53BX02) has insecticidal properties. The effects are due to binding to … Nitenpyram
Products Rabeprazole is commercially available in the form of film-coated tablets (Pariet, generic). It has been approved in many countries since 1999. Generic versions have been available since 2012. Structure and properties Rabeprazole (C18H21N3O3S, Mr = 359.4 g/mol) is a benzimidazole and pyridine derivative and a racemate. It is present in drugs as rabeprazole sodium, … Rabeprazole
Products Flupirtine is not approved as a drug in many countries. In some European countries, it was commercially available in the form of capsules and suppositories (e.g., Katadolon, Trancopal Dolo), among others. In Germany, flupirtine had been registered since 1989. In 2018, it was withdrawn from the market due to liver toxicity. Structure and properties … Flupirtine
Products Perampanel is commercially available in the form of film-coated tablets (Fycompa). It has been approved in many countries since late 2012. In 2020, an oral suspension was also registered. Structure and properties Perampanel (C23H15N3O, Mr = 349.4 g/mol) is a pyridine derivative. It exists in the drug as a white to yellowish powder that … Perampanel
Products Pheniramine is contained in combination with other active ingredients in NeoCitran powder, which has been approved in many countries since 1985. Structure and properties Pheniramine (C16H20N2, Mr = 240.3 g/mol) is present in drugs as pheniramine maleate, a white crystalline powder that is very soluble in water. It is a racemate and an alkylamine … Pheniramine
Products Cerivastatin was commercially available in the form of film-coated tablets (Lipobay, Baycol). Because of rare possible adverse effects, it was withdrawn from the market in August 2001 (see below). Structure and properties Cerivastatin (C26H34FNO5, Mr = 459.6 g/mol) is a pyridine derivative and is present in drugs as cerivastatin sodium. Unlike other statins, it … Cerivastatin
Products Pirbuterol is available as a drug for inhalation in some countries (e.g., USA, Maxair). The drug is no longer approved in many countries. Structure and properties Pirbuterol (C12H20N2O3, Mr = 240.3 g/mol) is a pyridine derivative closely related structurally to salbutamol (Ventolin, generics), differing from it only in one nitrogen atom. It is present … Pirbuterol
