Products Metronidazole is commercially available for the external treatment of rosacea as a cream (Rosalox, Perilox), a cream tinted with iron oxides (Perilox color), and a gel (Nidazea, Rozex). In some countries, e.g. Germany, a lotion is also available. The effectiveness of the therapy was first demonstrated by Nielsen in 1983. In many countries, the … Metronidazole for the External Treatment of Rosacea
Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs
Products Methylprednisolone aceponate has been approved in many countries since 1991 and is commercially available as cream, ointment, and fatty ointment (Advantan). Structure and properties Methylprednisolone aceponate (C27H36O7, Mr = 472.6 g/mol) is a lipophilic and nonhalogenated glucocorticoid that is hydrolyzed in the skin by esterases to the active metabolite 6α-methylprednisolone-17-propionate. Effects Methylprednisolone aceponate (ATC … Methylprednisolone Aceponate
Products Halcinonide was commercially available as a solution, cream, and fat cream, and was also combined fixedly with urea and salicylic acid (Betacorton, Betacorton S). It was approved in many countries in 1981. It was discontinued from 2018 to 2019. Structure and properties Halcinonide (C24H32ClFO5, Mr = 454.96 g/mol) exists as a white powder that … Halcinonide
Products Halometasone is commercially available as a cream in combination with triclosan (Sicorten plus). It has been approved in many countries since 1983. Structure and properties Halometasone (C22H27ClF2O5, Mr = 444.9 g/mol) is a chlorinated and fluorinated (halogenated) steroid. Effects Halometasone (ATC D07AC12) has anti-inflammatory, antiallergic, and immunosuppressive properties. It is a potent class III … Halometasone
Products Ivermectin is commercially available in some countries in tablet form (Stromectol). It has not yet been registered in many countries and therefore must be imported from abroad if needed. Ivermectin has been used medicinally since the 1980s, initially primarily as a veterinary drug. This article refers to peroral administration in humans. See also under … Ivermectin
Products The ivermectin cream Soolantra was approved in many countries in 2016 (US: 2014). Structure and properties Ivermectin is a mixture of the two ivermectin components H2B1a and H2B1b. The two molecules differ structurally only by a methylene group. Ivermectin exists as a white to yellowish white, crystalline and weakly hygroscopic powder. The macrocyclic lactone … Ivermectin Cream
Products Tretinoin is commercially available as a cream and lotion (Airol) and in capsule form (Vesanoid). It has been approved in many countries since 1973. The Retin-A cream and gel went out of commerce in many countries at the end of 2012 for commercial reasons. This article refers to external treatment. Structure and properties Tretinoin … Tretinoin
Exfoliation is a beauty treatment that removes dead skin cells from the skin to give the regrowing skin room to grow. It is said to make the skin look healthier and fresher. What is exfoliation? A peel is applied to the skin in the form of a cream or fluid, where it dissolves dead skin … Peeling: Treatment, Effect & Risks
Products Adapalene is commercially available as a cream and gel (Differin). It is also available in combination with benzoyl peroxide (Epiduo, Epiduo Forte). Adapalene has been approved in many countries since 1995. Structure and properties Adapalene (C28H28O3, Mr = 412.52 g/mol) is a synthetic derivative of naphthalic acid without the typical retinoid structure. It exists … Adapalene
Products Mometasone furoate is commercially available as a cream, ointment, emulsion, and solution (Elocom, Monovo, Ovixan). It has been approved in many countries since 1989. This article refers to use on the skin. Nasal sprays are also available; see mometasone nasal spray. In 2020, a fixed combination with indacaterol was approved for asthma therapy (Atectura … Mometasone
Products Fluprednidene acetate is commercially available as a cream in many countries and has been approved since 1993 (Decoderm bivalent + miconazole nitrate). Structure and properties Fluprednidene acetate (C24H29FO6, Mr = 432.5 g/mol) Effects Fluprednidene acetate (ATC D07AB07) has anti-inflammatory, antiallergic, antipruritic, and antiproliferative properties. The effects are due to binding to intracellular glucocorticoid receptors. … Fluprednidene Acetate
