Products Apalutamide was approved in the US and EU in 2018 and in many countries in 2019 in film-coated tablet form (Erleada). Structure and properties Apalutamide (C21H15F4N5O2S, Mr = 477.4 g/mol) exists as a white to slightly yellow powder that is practically insoluble in water. The active metabolite -demethylapalutamide is also active, but more weakly … Apalutamide
Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses
Products Emedastine is commercially available in the form of eye drops (Emadine). It has been approved in many countries since 1999. Structure and properties Emedastine (C17H26N4O, Mr = 302.41 g/mol) is a benzimidazole and a methyl diazepine derivative. It is present in drugs as emedastinidifumarate, a white powder that is soluble in water. Effects Emedastine … Emedastine
Products Perphenazine was commercially available in the form of film-coated tablets (Trilafon). It was approved in many countries in 1957 and went out of commerce on 3/31/2013. Structure and properties Perphenazine (C21H26ClN3OS, Mr = 403.9 g/mol) is a piperidine derivative of phenothiazine. It exists as a white to yellowish white crystalline powder that is practically … Perphenazine
Products Sotalol is commercially available in tablet form (generic). It has been approved in many countries since 1980. The original Sotalex is out of commerce. Structure and properties Sotalol (C12H20N2O3S, Mr = 272.4 g/mol) is present in drugs as sotalol hydrochloride, a racemate and white powder that is readily soluble in water. Sotalol is a … Sotalol
Products In medicine, drugs with the active ingredient atropine are mainly used. Preparations from the leaves are less common today. In alternative medicine, belladonna is widely used, but mainly in the form of strong homeopathic dilutions. Stem plant Belladonna, a member of the nightshade family (Solanaceae), is native to Europe. The genus name is derived … Belladonna: Medicinal Uses
Products Nebivolol is commercially available in tablet form as a monopreparation (Nebilet, generic, USA: Bystolic) and in combination with hydrochlorothiazide (Nebilet plus). The active ingredient has been approved in many countries since 1998. A fixed combination with valsartan is also available in some countries (Byvalson). Structure and properties Nebivolol (C22H25F2NO4, Mr = 405.4 g/mol) has … Nebivolol
Products Naftidrofuryl is commercially available in tablet form (Praxilene). It has been approved in many countries since 1982. Structure and properties Naftidrofuryl (C24H33NO3, Mr = 383.5 g/mol) is present in drugs as naftidrofuryl hydrogen oxalate, a white powder that is readily soluble in water. It is a mixture of 4 stereoisomers. Effects Naftidrofuryl (ATC C04AX21) … Naftidrofuryl: Drug Effects, Side Effects, Dosage and Uses
Products Nalbuphine is commercially available as a solution for injection (Nalbuphine OrPha). It has been approved in many countries since 2004. Structure and properties Nalbuphine (C21H27NO4, Mr = 357.4 g/mol) is a morphine derivative structurally related to naloxone and oxymorphone. It is present in drugs as nalbuphine hydrochloride. Effects Nalbuphine (ATC N02AF02) has analgesic properties. … Nalbuphin
Products Diphenhydramine is commercially available in tablet, drop, and gel forms (e.g., Benocten, Nardyl Sleep, Fenipic plus), among others. It is also known as Benadryl in some countries. Diphenhydramine was developed in the 1940s. It is also a component of the active ingredient dimenhydrinate. Structure and properties Diphenhydramine (C17H21NO, Mr = 255.4 g/mol) is present … Diphenhydramine
Products Lemborexant was approved in the United States in 2019 in film-coated tablet form (Dayvigo). This as the second agent in the orexin receptor antagonist group. Structure and properties Lemborexant (C22H20F2N4O2, Mr = 410.42 g/mol) is a pyrimidine and pyridine derivative. It exists as a white powder and is practically insoluble in water. Effects Lemborexant … Lemborexant
Products Mepyramine is commercially available as a gel, an external solution, and a spray. It is found exclusively in combination products, for example, Stilex and Parapic. Structure and properties Mepyramine (C17H23N3O, Mr = 285.38 g/mol) is present in drugs as mepyramine maleate, a white to slightly yellowish powder that is very soluble in water. It … Mepyramine