Ginger

Products Ginger is contained in various medicinal products. These include capsules, which are approved as medicinal products (Zintona). It is also available as a tea, as an open product, in the form of ginger candies and as candied ginger. Also available is the essential oil. Fresh ginger can be purchased in grocery stores. Stem plant … Ginger

Nabilon

Products Nabilone is commercially available in the United States, the United Kingdom, and Germany, for example, in the form of capsules (Cesamet, Canemes). It is a narcotic drug. In many countries, the drug is not registered. The active ingredient was developed in the 1970s. Structure and properties Nabilone (C24H36O3, Mr = 372.5 g/mol) is a … Nabilon

Netupitant, Palonosetron

Products The fixed combination of netupitant and palonosetron has been approved in capsule form (Akynzeo). The drug was released in many countries in 2015. Structure and properties Netupitant (C30H32F6N4O, Mr = 578.6 g/mol) is a fluorinated piperazine and pyrimidine derivative. Palonosetron (C19H24N2O, Mr = 296.4 g/mol) is present in drugs as palonosetron hydrochloride, a white … Netupitant, Palonosetron

Cyclizine

Product Cyclizine has been discontinued in many countries since 2008. Marzine is no longer available. Possible alternatives include the antihistamines dimenhydrinate or meclozine. Structure and properties Cyclizine (C18H22N2, Mr = 266.38 g/mol) is a piperazine derivative. In the drug, it is present as cyclizine hydrochloride. Effects Cyclizine (ATC R06AE03) has antihistamine, antiemetic, antivertiginous, and sedative … Cyclizine

Thiethylperazine

Products Thiethylperazine was commercially available in the form of dragées, as a solution for injection, and as suppositories (Torecan, Novartis). It had been approved in many countries since 1960. The suppositories went out of circulation in 2010 due to lack of demand. The other dosage forms were withdrawn from the market in 2014. Structure and … Thiethylperazine

Promazine

Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine

Promethazine

Products In many countries, drugs containing promethazine are currently no longer on the market. The last product to be withdrawn from the market was Rhinathiol promethazine with the expectorant carbocisteine on January 31, 2009. However, medicines are still available in many countries. The original drug is Phenergan. Promethazine was developed in the 1940s at Rhône-Poulenc, … Promethazine

Dimenhydrinate

Products Dimenhydrinate is commercially available in the form of tablets, dragées, [chewing gum dragées>chewing gum], and capsules, among others. Since 2012, a combination with the calcium channel blocker cinnarizine has been approved in many countries (Arlevert) see under Cinnarizine and Dimenhydrinate. Structure and properties Dimenhydrinate (C24H28ClN5O3, Mr = 470.0 g/mol) is the salt of diphenhydramine … Dimenhydrinate

Ondansetron

Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron

Penfluridol

Products Penfluridol is no longer available as a drug in many countries. Semap tablets are out of commerce. Structure and properties Penfluridol (C28H27ClF5NO, Mr = 523.96 g/mol) is a diphenylbutylpiperidine. Effects Penfluridol (ATC N05AG03) is potent antidopaminergic, antiemetic, and potent antipsychotic against hallucinations and delusions. It has minimal activity at the 5-HT2 receptor (antiserotonergic) and … Penfluridol

Perphenazine

Products Perphenazine was commercially available in the form of film-coated tablets (Trilafon). It was approved in many countries in 1957 and went out of commerce on 3/31/2013. Structure and properties Perphenazine (C21H26ClN3OS, Mr = 403.9 g/mol) is a piperidine derivative of phenothiazine. It exists as a white to yellowish white crystalline powder that is practically … Perphenazine

Cannabidiol

Products In many countries, there are currently no medicines approved that contain only cannabidiol. However, the active ingredient is a component of the cannabis oral spray Sativex, which is registered as a drug for MS treatment in many countries and also contains THC. The oral solution Epidiolex or Epidyolex was approved as a drug in … Cannabidiol