Dapsone

Products Dapsone is approved in Germany in tablet form (Dapsone-Fatol). In the USA, it is additionally on the market as a gel for the treatment of acne (Aczone). No preparations are currently registered in many countries. Structure and properties Dapsone or 4,4′-diaminodiphenylsulfone (C12H12N2O2S, Mr = 248.3 g/mol) is a sulfone and aniline derivative with structural … Dapsone

Hydroxychloroquine

Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine

Ornidazole

Products Ornidazole is commercially available in the form of film-coated tablets and ampoules (Tiberal). It has been approved in many countries since 1980. Vaginal tablets for local treatment of trichomoniasis are out of commerce. Structure and properties Ornidazole (C7H10ClN3O3, Mr = 219.6 g/mol) is a nitroimidazole. Effects Ornidazole (ATC P01AB03, ATC J01XD03) has bactericidal and … Ornidazole

Peru Balsam

Products Peru balsam is found in many countries in cold ointments, balm sticks and lip balms (Dermophil India, Peru Stick), traction ointments (Leucen) and healing ointments (Rapura, Zeller Balsam), among others. The majority of these are traditional medicines that have been on the market for decades. Some medicines also contain an artificially produced Peru balsam, … Peru Balsam

Nifurtimox

Products No finished drug products containing nifurtimox are on the market in many countries. Lampit is not approved in many countries. Structure and properties Nifurtimox (C10H13N3O5S, Mr = 287.3 g/mol) is a nitrofuran derivative. Effects Nifurtimox (ATC P01CC01) has antiparasitic properties. The effects are due to the formation of free radicals. Indications For the treatment … Nifurtimox

Annual Mugwort

Stem plant Asteraceae, annual mugwort. see also under common mugwort. Medicinal drug Artemisiae herba – Mugwort herb. Ingredients Sesquiterpenes: artemisinin. Chemical derivatives: artemether, arteether, artelinate, artesunate. Effects Antiparasitic against plasmodia. Indications for use Malaria (pure substance and chemical derivatives). Dosage In finished drug products: Artemether (Riamet + lumefantrine).

Aminonitrothiazole

Products Aminonitrothiazole is commercially available in the form of tablets for aquarium use. It has been approved in many countries since 2007 and only as a veterinary drug. Structure and properties Aminonitrothiazole (C3H3N3O2S, Mr = 145.1 g/mol) is a nitrated thiazole. It exists as an odorless powder and has a greenish-yellow to orange-yellow color and … Aminonitrothiazole

Atovaquone: Effects, Uses & Risks

Atovaquone is one of the most important drugs for the prevention and treatment of malaria tropica. It is considered equally effective and rich in side effects and is usually used in conjunction with other preparations. It can be administered by a physician or by the patient and is regal orally. What is atovaquone? Atovaquone is … Atovaquone: Effects, Uses & Risks

Antifungals

Products Antifungal products are commercially available as creams, ointments, powders, solutions, tablets, capsules, and injectables, among others. Structure and properties The antifungal agents are a structurally heterogeneous class of agents. However, several groups can be identified within the antifungals, such as the azole antifungals and the allylamines (see below). Effects Antifungals have antifungal, fungistatic, or … Antifungals

Chinese Tree

Stem plant Vahl, Rubiaceae, China tree. Medicinal drug Cinchonae cortex – cinchona bark: the whole or cut bark of Vahl ( Pavon), of (Weddell), of (Moens ex Trimen), of their varieties and hybrids (PhEur). The PhEur requires a minimum content of alkaloids. Preparations Cinchonae extractum ethanolicum liquidum Ingredients Alkaloids: quinine, quinidine, cinchonine, cinchonidine. Tannins Effects … Chinese Tree

Quinine

Products Quinine is approved in many countries in the form of dragées for malaria therapy (quinine sulfate 250 Hänseler). In Germany, film-coated tablets of 200 mg quinine sulfate are commercially available for the treatment of calf cramps (Limptar N). Structure and properties Quinine (C20H24N2O2, Mr = 324.4 g/mol) usually exists as quinine sulfate, a white … Quinine

Mesulfen

Products Mesulfen was formerly included in Soufrol Sulfur Oil Bath, which also contained kerosene and excipients. It was approved in many countries in 1967. Since 2016, Soufrol no longer contains mesulfen, but colloidal sulfur. Structure and properties Mesulfen (C14H12S2, Mr = 244.38 g/mol) is an organic sulfur compound. Effects Mesulfen (ATC D10AB05, ATC P03AA03) has … Mesulfen