Valganciclovir: Effects, Uses & Risks

Valganciclovir is a virostatic agent used to treat cytomegalovirus retinitis (inclusion body disease) occurring in AIDS patients. The drug belongs to the group of nucleoside analogues and is widely used. As a prodrug of the substance ganciclovir, it has essentially the same effects and side effects as the latter. What is valganciclovir? Valganciclovir is a … Valganciclovir: Effects, Uses & Risks

Valganciclovir

Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir

Didanosine

Products Didanosine was commercially available in the form of capsules (Videx EC). It was first approved in 1991 as the second HIV drug after AZT (EC = enteric coated, capsules filled with enteric granules). Structure and properties Didanosine (C10H12N4O3, Mr = 236.2 g/mol) corresponds to 2′,3′-dideoxyinosine, a synthetic nucleoside analog of deoxyadenosine. The 3′-hydroxy group … Didanosine

Ganciclovir

Products Ganciclovir is commercially available as a lyophilizate for the preparation of an infusion solution (Cymevene). It has been approved in many countries since 1988. Furthermore, an ophthalmic gel was registered in 2020. Structure and properties Ganciclovir (C9H13N5O4, Mr = 255.2 g/mol) is present in drugs as ganciclovir sodium, a white crystalline powder that is … Ganciclovir

Three Day Fever

Symptoms Three-day fever is most common in infants 6-12 months of age and in young children. Newborns are still protected thanks to maternal antibodies. After an incubation period of 5-15 days, the disease begins with sudden onset and high fever that lasts for 3-5 days. Febrile convulsions are a known and comparatively frequent complication (about … Three Day Fever

Ganciclovir: Effects, Uses & Risks

Ganciclovir is the name given to a virostatic agent. It is effective against herpes viruses. What is ganciclovir? Ganciclovir is an analog of the nucleic base guanine. As a virostatic agent, it is used to treat infections caused by herpes viruses. The active ingredient was approved in Europe in the 1980s. In Germany, the drug … Ganciclovir: Effects, Uses & Risks

Mycophenolate Mofetil

Products Mycophenolate mofetil is commercially available in the form of film-coated tablets, capsules, as an injectable, and as a suspension (CellCept, generics). It has been approved in many countries since 1995. Structure and properties Mycophenolate mofetil (C23H31NO7, Mr = 433.5 g/mol) exists as a white crystalline powder and is practically insoluble in water. It is … Mycophenolate Mofetil

Imipenem

Products Imipenem is commercially available as an infusion preparation and fixed combination with cilastatin (Tienam, generics). Imipenem was approved in many countries in 1985 as the first member of the carbapenems. Structure and properties Imipenem (C12H17N3O4S, Mr = 299.3 g/mol) is present in drugs as imipenem monohydrate, a white or pale yellow powder that is … Imipenem