Products Alirocumab was approved in the United States in 2015 as the first agent in the group of PCSK9 inhibitors in the form of a solution for injection (Praluent). Evolocumab (Repatha) followed as the second agent in the EU, also in 2015. Structure and properties PCSK9 inhibitors to date are monoclonal antibodies that must be … PCSK9 Inhibitors
Products Degarelix is commercially available as a powder and solvent for solution for injection (Firmagon). It was approved in many countries in February 2010. Structure and properties Degarelix is a decapeptide derived from gonadotropin-releasing hormone (GnRH), a hormone of the hypothalamus. It is present in drugs as degarelix acetate and differs from the natural substance … Degarelix
Products Delafloxacin was approved in the United States in 2017, in the EU in 2019, and in many countries in 2020 as a powder for a concentrate for solution for infusion and in tablet form (Quofenix). Structure and properties Delafloxacin (C18H12ClF3N4O4, Mr = 440.8 g/mol) belongs to the group of fluoroquinolones. It is present in … Delafloxacin
Products Delavirdin is commercially available in the United States under the brand name Rescriptor. It is not commercially available in many countries. Structure and properties Delavirdine (C22H28N6O3S, Mr = 456.6 g/mol) Effects Delavirdine (ATC J05AG02) is antiviral and an inhibitor of HIV reverse transcriptase. Indications HIV
Products No medicines containing delorazepam are registered in many countries. In Italy, products available include EN drops and tablets and generics. Structure and properties Delorazepam (C15H10Cl2N2O, Mr = 305.2 g/mol) is a chlorinated and demethylated diazepam (Valium) related to lorazepam (Temesta). Effects Delorazepam (ATC N05BA) has antianxiety, sedative, anticonvulsant, and sleep-inducing properties. It crosses the … Delorazepam
Products Oxymetazoline cream was approved in the United States in 2017 (Rhofade, 1%). Oxymetazoline is also available as a nasal spray at a lower concentration (Nasivin); see Oxymetazoline. Structure and properties Oxymetazoline (C16H24N2O, Mr = 260.4 g/mol) is present in drugs as oxymetazoline hydrochloride, a white crystalline powder that is readily soluble in water. It … Oxymetazoline Cream
Products Oxymorphone is commercially available in the United States as tablets and sustained-release tablets and has also been administered parenterally and rectally. It is not registered in many countries. Oxymorphone has been approved in the U.S. since 1959 (brand names: Numorphan, Opana, Opana ER, generics). It is a narcotic drug. Due to the potential for … Oxymorphone
Products Citriodiol is commercially available in the form of sprays (e.g. Anti-Brumm Naturel, Anti-Brumm Tick Stop + Icaridin), among others. Structure and properties Citriodiol is produced from an extract of leaves of lemon eucalyptus, also called (family: Myrtaceae). A major active ingredient is -menthane-3,8-diol (PMD, C10H20O2, Mr = 172.3 g/mol). Effects Citriodiol protects between 6-8 … Citriodiol
Products Citronella oil is commercially available in the form of sprays, bracelets, fragrance lamps and as pure essential oil, among other products. Structure and properties Citronella oil is the essential oil obtained by steam distillation from the fresh or partially dried aerial parts of (PhEur). It exists as a pale yellow to brownish yellow liquid … Citronella Oil
Products Budesonide is commercially available as a monopreparation for inhalation as a powder inhaler and suspension (Pulmicort, generics). It is also combined fixed with formoterol (Symbicort Turbuhaler, Vannair Dosage Aerosol). This article refers to monotherapy. Budesonide has been approved in many countries since 1988. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a … Budesonide (Inhalation)
Products Citrulline is commercially available in the form of sachets containing a drinkable solution (Biostimol). It has been approved in many countries since 1996. Structure and properties L-(+)-citrulline (C6H13N3O3, Mr = 175.2 g/mol) exists as a white crystalline powder that is readily soluble in water. Citrulline is an amino acid found, for example, in watermelon. … Citrulline
Products Budesonide sustained-release capsules have been approved in many countries since 1998 (Entocort CIR, Budenofalk). Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Effects Budesonide (ATC R03BA02) has anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are … Budesonide Capsules
